ETFs Holding NBIX

Nuveen Quant Mid Cap Growth Fund Class A

Nuveen Quant Mid Cap Growth Fund Retirement Class

Nuveen Quant Mid Cap Growth Fund Class R6

Thompson MidCap Fund

VanEck Biotech ETF

Alger Russell Innovation ETF

FT Vest Growth Strength & Target Income ETF

Janus Henderson Mid Cap Growth Alpha ETF

Bushido Capital US Equity ETF

NYLI Fiera SMID Growth Fund Class R6

NYLI Fiera SMID Growth Fund Investor Class

First Trust Health Care AlphaDEX Fund

Franklin Biotechnology Discovery Fund Class C

Franklin Biotechnology Discovery Fund Advisor Class

AMG Renaissance Large Cap Growth Fund Class N

FullerThaler Behavioral Small-Mid Core Equity Fund Class A

FullerThaler Behavioral Small-Mid Core Equity Fund Institutional Class

Calvert Small/Mid-Cap Fund Class I

Calvert Small/Mid-Cap Fund Class C

First Trust Innovation Leaders ETF

AMG GW&K Small/Mid Cap Fund Class I

AMG GW&K Small/Mid Cap Fund Class Z

Rydex Biotechnology Fund Class A

Rydex Biotechnology Fund Class H

Eaton Vance Worldwide Health Sciences Fund Cl C

Eaton Vance WorldWide Health Sciences Fund Class R

Nomura Healthcare Fund Class C

Nomura Healthcare Fund Institutional Class

JPMorgan Mid Cap Growth Fund Class I

JPMorgan Mid Cap Growth Fund Class R6

JPMorgan Mid Cap Growth Fund Class R2

JPMorgan Mid Cap Growth Fund Class C

Virtus Silvant Small/Mid Growth ETF

Loomis Sayles Small/Mid Cap Growth Fund Class N

Impax Small Cap Fund CLASS A

Impax Small Cap Fund INSTITUTIONAL CLASS

NAA Mid Growth Fund Class A

iShares Biotechnology ETF

First Trust SMID Growth Strength ETF

Timothy Plan Free Cash Flow ETF

Brown Advisory Sustainable Small-Cap Core Fund Class Investor

DWS Small Cap Growth Fund Class C

DWS Small Cap Growth Fund Class S

Allspring LT Large Growth ETF

WisdomTree US MidCap Quality Growth Fund

Commerce Funds Midcap Growth Fund

Horizon Multi-Factor Small/Mid Cap Fund Investor Class

BlackRock Health Sciences Term Trust

Allspring SMID Cap Growth Fund Administrator Class

Allspring SMID Cap Growth Fund Institutional Class

Nomura Smid Cap Core Fund Class R6

Nomura Smid Cap Core Fund Class A

Nomura Smid Cap Core Fund Class Y

AQR LSE Fusion Fund Class I

AQR LSE Fusion Fund Class R6

Global X Aging Population ETF

Vanguard S&P Mid-Cap 400 Growth ETF

Hood River New Opportunities Fund Retirement Class

Hood River New Opportunities Fund Investor Class

JPMorgan Growth Advantage Fund Class C

JPMorgan Growth Advantage Fund Class R2

JPMorgan Growth Advantage Fund Class R5

JPMorgan Growth Advantage Fund Class R3

Invesco NASDAQ Next Gen 100 ETF

S&P MidCap 400 Pure Growth Fund Class C

Biotechnology UltraSector ProFund Service Class

Distillate US Fundamental Stability & Value ETF

VictoryShares Free Cash Flow Growth ETF

Motley Fool Next Index ETF

Convergence Long/Short Equity ETF

Xtrackers S&P MidCap 400 Scored & Screened ETF

Vanguard Wellington US Value Active ETF

Anydrus Advantage ETF

Columbia Acorn Trust Acorn Fund Class I

Columbia Acorn Trust Acorn Fund Institutional II Class

Carillon Scout Mid Cap Fund Class A

Carillon Scout Mid Cap Fund Class C

Allspring Diversified Capital Builder Fund Class C

Columbia Acorn Trust Acorn Fund Class A

Carillon Scout Mid Cap Fund Class I

Carillon Eagle Mid Cap Growth Fund Class A

Carillon Eagle Mid Cap Growth Fund Class I

Hussman Strategic Growth Fund

First Trust Mid Cap Growth AlphaDEX Fund

AQR Large Cap Defensive Style Fund Class N

Virtus Silvant Mid-Cap Growth Fund Institutional Class

Virtus Silvant Mid-Cap Growth Fund Class C

Virtus Silvant Mid-Cap Growth Fund Class R6

Thrivent Small Cap Growth Fund Class S

Voya Index Plus MidCap Portfolio Class S

VALIC Company I Capital Appreciation Fund

Mercer US Small/Mid Cap Equity Fund Class I

DWS Health and Wellness Fund Class A

DWS Health and Wellness Fund Class Institutional

Columbia Integrated Large Cap Value Fund Class Institutional

AQR Long-Short Equity Fund Class I

NYLI Candriam US Mid Cap Equity ETF

Victory Mid-Cap Core Growth Fund Class R6

Victory Mid-Cap Core Growth Fund Class Y

iShares Morningstar Small-Cap Growth ETF

AQR Equity Market Neutral Fund Class I

BlackRock Mid-Cap Value Fund Institutional

BlackRock Mid-Cap Value Fund Class A

BlackRock Mid-Cap Value Fund Class R

Hussman Strategic Allocation Fund

Vanguard Windsor Fund Admiral Shares

Brown Advisory Small Cap Growth Fund Adv Shares

American Beacon Man Large Cap Growth Fund Class A

American Beacon Man Large Cap Growth Fund Investor Class

American Beacon Man Large Cap Growth Fund Y Class

Rydex Health Care Fund Class H

Rydex Health Care Fund Investor Class

State Street SPDR S&P MIDCAP 400 ETF Trust

AQR MS Fusion Fund Class N

FlexShares US Quality Low Volatility Index Fund

Vanguard S&P Mid-Cap 400 ETF

Vanguard Small Cap Growth ETF

Dodge & Cox Stock Fund

JPMorgan Active Growth ETF

Hood River Small Cap Growth Fund Institutional Class

Vanguard Small Cap Growth Index Fund Investor Class

Vanguard Small Cap Growth Index Fund Institutional

MFS New Discovery Fund Class A

MFS New Discovery Fund Class R1

MFS New Discovery Fund Class R2

MFS New Discovery Fund Class R4

MFS New Discovery Fund Class I

iShares Russell Midcap Growth ETF

Empower S&P Mid Cap 400 Index Fund Investor Class

Northern Funds Mid Cap Index Portfolio

Strive Mid Cap ETF

Federated Hermes Mid-Cap Index Fund Class R6

Federated Hermes Mid-Cap Index Fund Service Class

John Hancock Variable Insurance Trust Mid Index Trust Series Nav

John Hancock Variable Insurance Trust Mid Cap Index Trust Series I

JPMorgan Mid Cap Equity Fund Class R2

JPMorgan Mid Cap Equity Fund Class R6

BNY Mellon Midcap Index Fund, Inc Investor Class

Principal MidCap S&P 400 Index Fund Class J

Principal MidCap S&P 400 Index Fund R-3 Class

State Street SPDR Portfolio S&P 400 Mid Cap ETF

Fidelity Mid Cap Growth Index Fund

Voya Russell Mid Cap Growth Index Portfolio Class S2

S&P MidCap Index Fund Class K

S&P MidCap Index Fund Investor Class

JPMorgan BetaBuilders US Mid Cap Equity ETF

Columbia Mid Cap Index Fund Institutional II Class

Mid-Cap Growth ProFund Service Class

Columbia Mid Cap Index Fund Class A

Vanguard S&P Mid-Cap 400 Index Fund Institutional Class

Janus Henderson Global Life Sciences Fund Class T

Janus Henderson Global Life Sciences Fund Class C

Janus Henderson Global Life Sciences Fund Class N

Janus Henderson Global Life Sciences Fund Class D

SIMT Tax-Managed Managed Volatility Fund Class Y

Columbia Integrated Large Cap Growth Fund Class Institutional II

Columbia Integrated Large Cap Growth Fund Class Institutional Class III

Mid-Cap ProFund

AQR Style Premia Alternative Fund Class R6

Sofi Next 500 ETF

Franklin Global Allocation Fund Class C

Franklin Global Allocation Fund Class R

Nuveen Quant Small/Mid Cap Equity Fund Class A

Nuveen Quant Small/Mid Cap Equity Fund Retirement Class

Nuveen Quant Small/Mid Cap Equity Fund Class W

Direxion Daily Mid Cap Bull 3X ETF

Fidelity Flex Mid Cap Index Fund

Vanguard Explorer Fund Investor Class

Fidelity Enhanced Mid Cap Core ETF

Yorktown Growth Fund Class A

American Century Disciplined Value Fund R class

American Century Disciplined Value Fund Class I

Yorktown Growth Fund Class L

American Century Disciplined Value Fund Investor Class

Hartford Capital Appreciation HLS Fund Class IA

SGI US Large Cap Equity Fund Class A

Pace Small/Med Company Growth Equity Investments Fund Class A

SGI US Large Cap Equity Fund Class I

John Hancock Variable Insurance Trust Health Sciences Trust Series II

John Hancock Variable Insurance Trust Health Sciences Trust Series I

Mid-Cap 1.5x Strategy Fund Class C