ETFs Holding CYTK

Invesco Dorsey Wright Healthcare Momentum ETF

Columbia Select Small Cap Value Fund Class I3

Columbia Select Small Cap Value Fund Class A

AMG GW&K Small Cap Value Fund Class N

AMG GW&K Small Cap Value Fund Class Z

Baron Health Care Fund Institutional Shares

T.Rowe Price Institutional Small-Cap Stock Fund

T. Rowe Price Small Cap Stock Fund, Inc Class I

T. Rowe Price Small Cap Stock Fund, Inc Class Z

Rydex Biotechnology Fund Class A

Rydex Biotechnology Fund Class H

Goldman Sachs Small Cap Equity ETF

Segall Bryant & Hamill Small Cap Growth Fund Retail Class

Impax Small Cap Fund INVESTOR CLASS

Janus Henderson Small Cap Growth Alpha ETF

Thornburg Investment Trust Small/Mid Cap Growth Fd Cl R4

Thornburg Investment Trust Small/Mid Cap Growth Fd Cl R3

Thornburg Investment Trust Small/Mid Cap Growth Fd Cl I

Principal SmallCap Fund Class J

Principal SmallCap Fund Class R-5

Principal SmallCap Fund Class R6

Columbia Small Cap Value and Inflection Fund Class A

Columbia Small Cap Value and Inflection Fund Institutional Class III

Columbia Small Cap Value and Inflection Fund Class S

Biotechnology UltraSector ProFund

Fidelity Advisor Biotechnology Fund Class C

Fidelity Advisor Biotechnology Fund Class M

AlphaCentric Life Sciences and Healthcare Fund Class A

AlphaCentric Life Sciences and Healthcare Fund Class I

John Hancock Variable Insurance Trust Small Company Value Trust Series I

Virtus LifeSci Biotech Clinical Trials ETF

Brown Advisory Small Cap Growth Fund Adv Shares

AB Small Cap Value Portfolio

AB Small Cap Value Portfolio

T. Rowe Price Small Cap Value Fund Investor Class

T. Rowe Price Small Cap Value Fund Z Class

Carillon Chartwell Small Cap Fund Class A

Carillon Chartwell Small Cap Fund Class R-6

T. Rowe Price Capital Appreciation Premium Income ETF

William Blair Small Cap Growth Fund Class R6

Carillon Chartwell Small Cap Growth Fund Class A

Carillon Chartwell Small Cap Growth Fund Class I

First Trust Mid Cap Growth AlphaDEX Fund

MoA Small Cap Value Fund

Vanguard Health Care Fund

AMG GW&K Small Cap Core Fund Class I

Hartford Healthcare HLS Fund Class IB

Goldman Sachs Small Cap Value Fund Class R

Goldman Sachs Small Cap Value Fund Class C Shares

Goldman Sachs Small Cap Value Fund Service Shares

Goldman Sachs Small Cap Value Fund Institutional Shares

iShares Russell 2000 Value ETF

William Blair Small-Mid Cap Growth Fund Class R6

JPMorgan Small Cap Growth Fund Class R4

JPMorgan Small Cap Growth Fund Class R6

JPMorgan Small Cap Growth Fund Class L

JPMorgan Small Cap Growth Fund Class I

JPMorgan Small Cap Growth Fund Class A

Fidelity Advisor Health Care Fund Class M

Fidelity Advisor Health Care Fund Class I

Fidelity Select Health Care Portfolio

MFS New Discovery Fund Class C

MFS New Discovery Fund Class B

MFS New Discovery Fund Class R6

MFS New Discovery Fund Class R3

BNY Mellon Small/Mid Cap Growth Fund Class A

BNY Mellon Small/Mid Cap Growth Fund Class Y

Fidelity Select Biotechnology Portfolio

Federated Hermes Kaufmann Small Cap Fund Class R6

Federated Hermes Kaufmann Small Cap Fund Class A

Federated Hermes Kaufmann Small Cap Fund Class R

Goldman Sachs Small/Mid-Cap Growth Fund Service Class

Goldman Sachs Small/Mid-Cap Growth Fund Inst Cl

Goldman Sachs Small/Mid-Cap Growth Fund Class R

Goldman Sachs Small/Mid-Cap Growth Fund Investor Class

The Hartford Healthcare Fund Class A

The Hartford Healthcare Fund Class C

The Hartford Healthcare Fund Cl R4

The Hartford Healthcare Fund Cl R5

The Hartford Healthcare Fund Class Y

John Hancock Variable Insurance Trust Capital Appreciation Value Trust Series Nav

Direxion Daily S&P Biotech Bull 3X ETF

Fidelity Advisor Stock Selector Small Cap Fund Class C

Fidelity Advisor Stock Selector Small Cap Fund Class M

Franklin Small Cap Growth Fund Class A

Franklin Small Cap Growth Fund Advisor Class

Fidelity Advisor Stock Selector Small Cap Fund Class Z

Federated Hermes Kaufmann Fund Class R

Federated Hermes Kaufmann Fund Institutional Class

Nuveen ESG Small-Cap ETF

Sofi Next 500 ETF

Hartford Small Company HLS Fund Class IA

John Hancock Variable Insurance Trust Small Stock Trust Series Nav

Empower T. Rowe Price Mid Cap Growth Fund Invoice Class

T. Rowe Price Capital Appreciation Fund Advisor Class

T. Rowe Price Mid-Cap Growth Portfolio Class II

T. Rowe Price Capital Appreciation Fund Class I

Empower Small Cap Growth Fund Investor Class

John Hancock Variable Insurance Trust Health Sciences Trust Series II

John Hancock Variable Insurance Trust Health Sciences Trust Series I

T. Rowe Price Institutional Mid-Cap Equity Growth Fund

T. Rowe Price Mid-Cap Growth Fund Class I

T. Rowe Price Mid-Cap Growth Fund Class z

Goldman Sachs Small/Mid Cap Value Fund Class R6

Goldman Sachs Small/Mid Cap Value Fund Investor Class

Goldman Sachs Small/Mid Cap Value Fund Class R

Goldman Sachs Small/Mid Cap Value Fund Class P Shares

Fidelity Series Small Cap Core Fund

MFS Blended Research Small Cap Equity Fund Class A

MFS Blended Research Small Cap Equity Fund Class I

MFS Blended Research Small Cap Equity Fund Class R1

MFS Blended Research Small Cap Equity Fund Class R3

MFS Blended Research Small Cap Equity Fund Class R6

T. Rowe Price Health Sciences Portfolio Class II

Calamos Timpani Small Cap Growth Fund Class A

Calamos Timpani Small Cap Growth Fund Class R6

Fidelity Advisor Small Cap Growth Fund Class C

Fidelity Advisor Small Cap Growth Fund

Fidelity Advisor Small Cap Growth Fund Class Z

Fidelity Advisor Small Cap Fund Class A

Fidelity Advisor Small Cap Fund Class I

Fidelity Advisor Small Cap Fund Class Z

The Hartford Small Company Fund Class C

The Hartford Small Company Fund Class F

The Hartford Small Company Fund Class R3

The Hartford Small Company Fund Class R5

Calamos Timpani Small Cap Growth Fund Class C

Hartford Small Cap Growth HLS Fund Class IA

JPMorgan Small Cap Value Fund Class R5

JPMorgan Small Cap Value Fund Class R6

JPMorgan Small Cap Value Fund Class C

JPMorgan Small Cap Value Fund Class A

T. Rowe Price Health Sciences Fund Class I

Vanguard Russell 2000 Value ETF

American Century Small Cap Growth Fund Class A

American Century Small Cap Growth Fund R6 Cl

American Century Small Cap Growth Fund R5 Class

American Century Small Cap Growth Fund I Class

American Century Small Cap Growth Fund Y Class

The Hartford Small Cap Growth Fund Class C

The Hartford Small Cap Growth Fund Class R3

The Hartford Small Cap Growth Fund Class R4

The Hartford Small Cap Growth Fund Class R5

Goldman Sachs Small Cap Growth Fund Class P

Goldman Sachs Small Cap Growth Fund Class C

Goldman Sachs Small Cap Growth Fund Class A

Rydex Health Care Fund Class H

Rydex Health Care Fund Investor Class

NYLI Candriam US Mid Cap Equity ETF

Voya Small Cap Growth Fund Class I

VALIC Company I Small Cap Value Fund

Voya Small Cap Growth Fund Class C

Voya Small Cap Growth Fund Class W

MassMutual Small Cap Growth Equity Fund Class A

MassMutual Small Cap Growth Equity Fund Service Class

MassMutual Small Cap Growth Equity Fund Administrative Class

MassMutual Small Cap Growth Equity Fund Class R5

John Hancock Multifactor Small Cap ETF

MassMutual Mid Cap Growth Fund Class R4

MassMutual Mid Cap Growth Fund Service Class

MassMutual Mid Cap Growth Fund Class R5

MassMutual Mid Cap Growth Fund Class Y

Columbia Integrated Small Cap Growth Fund Class Institutional

Fidelity Flex Mid Cap Focused Index Fund

Invesco Small Cap Growth Fund Class A

Invesco Small Cap Growth Fund Class R6

Invesco Small Cap Growth Fund Class R

Invesco Small Cap Growth Fund Class Y

Vanguard S&P Mid-Cap 400 Growth ETF

Franklin Biotechnology Discovery Fund Class A

Franklin Biotechnology Discovery Fund Class R6

Vanguard S&P Mid-Cap 400 ETF

State Street SPDR S&P MIDCAP 400 ETF Trust

Russell Investments US Small Cap Equity ETF

VY T. Rowe Price Capital Appreciation Portfolio S2

VY T. Rowe Price Capital Appreciation Portfolio Advisor Class

VY T. Rowe Price Capital Appreciation Portfolio Class R6

ProShares Russell 2000 High Income ETF

JPMorgan Small Cap Blend Fund Class R6

Nuveen Small Cap Blend Index Fund Retirement Class

JPMorgan Small Cap Blend Fund Class C