ETFs Holding IONS

Eventide Healthcare & Life Sciences Fund Class C

Eventide Healthcare & Life Sciences Fund Class N

Tweedy Browne International Value Fund II

Artisan Small Cap Fund Institutional Shares

Invesco Dorsey Wright Healthcare Momentum ETF

Victory RS Select Growth Fund Class A

Victory RS Select Growth Fund Class R6

ARK Genomic Revolution ETF

Franklin Biotechnology Discovery Fund Class A

Franklin Biotechnology Discovery Fund Class R6

Nomura Mid Cap Growth Fund Class R6

Nomura Mid Cap Growth Fund Class A

Nomura Mid Cap Growth Fund Class Y

First Trust Health Care AlphaDEX Fund

Rydex Biotechnology Fund Class C

Rydex Biotechnology Fund Investor Class

AMG GW&K Small Cap Growth Fund Class N

Dinosaur Lisanti Small Cap Growth Fund

Timothy Plan Small/Mid Cap Growth Fund Class C

RBC Global Opportunities Fund Class I

RBC Global Opportunities Fund Class A

Goldman Sachs Small/Mid-Cap Growth Fund Service Class

Goldman Sachs Small/Mid-Cap Growth Fund Inst Cl

Goldman Sachs Small/Mid-Cap Growth Fund Class R

Goldman Sachs Small/Mid-Cap Growth Fund Investor Class

American Century Select Fund R6 Class

American Century Select Fund Class G

American Century Select Fund Y Class

American Century Select Fund Investor Class

MFS New Discovery Fund Class A

MFS New Discovery Fund Class R1

MFS New Discovery Fund Class R2

MFS New Discovery Fund Class R4

MFS New Discovery Fund Class I

American Funds US Small & Mid Cap Equity Fund Class 529-C

American Funds US Small & Mid Cap Equity Fund Class 529-F-1

American Funds US Small & Mid Cap Equity Fund Class 529-F-3

American Funds US Small & Mid Cap Equity Fund Class R2E

American Funds US Small & Mid Cap Equity Fund Class R3

American Funds US Small & Mid Cap Equity Fund Class R5

American Funds US Small & Mid Cap Equity Fund Class R6

American Funds US Small & Mid Cap Equity Fund Class C

American Funds US Small & Mid Cap Equity Fund Class F2

State Street SPDR S&P Biotech ETF

Artisan International Small-Mid Fund Institutional Class

BlackRock Health Sciences Term Trust

Virtus LifeSci Biotech Products ETF

Biotechnology UltraSector ProFund

Goldman Sachs Mid Cap Growth Fund Class C

Goldman Sachs Mid Cap Growth Fund Institutional Shares

Goldman Sachs Mid Cap Growth Fund Service Shares

Goldman Sachs Mid Cap Growth Fund Class R6

Empower T. Rowe Price Mid Cap Growth Fund Invoice Class

Nuveen ESG Small-Cap ETF

Invesco Nasdaq Biotechnology ETF

T. Rowe Price Mid-Cap Growth Portfolio

T. Rowe Price Mid-Cap Growth Fund Advisor Class

T. Rowe Price Mid-Cap Growth Fund Class I

T. Rowe Price Mid-Cap Growth Fund Class z

Victory RS Mid Cap Growth Fund Class C

Victory RS Mid Cap Growth Fund Class R6

Victory RS Mid Cap Growth Fund Class A

Nuveen Mid Cap Growth Opportunities Fund Class R6

Kennedy Capital Small Cap Growth Fund Class Institutional

AMG GW&K Small/Mid Cap Fund Class N

Tweedy, Browne Insider + Value ETF

Hartford Healthcare HLS Fund Class IB

The Hartford Healthcare Fund Class A

The Hartford Healthcare Fund Class C

The Hartford Healthcare Fund Cl R4

The Hartford Healthcare Fund Cl R5

The Hartford Healthcare Fund Class Y

Fidelity Growth Company Fund

Putnam Small Cap Growth Fund Class A

Putnam Small Cap Growth Fund Class R6

Putnam Small Cap Growth Fund Class Y

Vanguard Health Care Fund

American Funds The New Economy Fund Class A

American Funds The New Economy Fund Class C

American Funds The New Economy Fund other Class

American Funds The New Economy Fund Class 529-F-2

American Funds The New Economy Fund Class 529-F-3

Invesco Small Cap Growth Fund Class C

Invesco Small Cap Growth Fund Investor Class

Invesco Small Cap Growth Fund Class R5

American Funds The New Economy Fund Other Class

American Funds The New Economy Fund Class R3 Shares

American Funds The New Economy Fund Class R4 Shares

American Funds The New Economy Fund Class R5E

American Funds The New Economy Fund Class R2E

John Hancock Variable Insurance Trust Health Sciences Trust Series Nav

Fidelity Select Biotechnology Portfolio

Goldman Sachs Small Cap Growth Fund Institutional Shares

Goldman Sachs Small Cap Growth Fund Class R6

Goldman Sachs Small Cap Growth Fund Investor Shares

Capital Group US Small and Mid Cap ETF

Invesco Health Care Fund Class A

Invesco Health Care Fund Class R

Invesco Health Care Fund Class R6

MassMutual Mid Cap Growth Fund Class R4

MassMutual Mid Cap Growth Fund Service Class

MassMutual Mid Cap Growth Fund Class R5

MassMutual Mid Cap Growth Fund Class Y

T. Rowe Price Health Sciences Portfolio Class II

T. Rowe Price Health Sciences Fund Class I

Invesco Main Street Mid Cap Fund CLASS C

Invesco Main Street Mid Cap Fund Class R

Invesco Main Street Mid Cap Fund CLASS Y

Invesco NASDAQ Next Gen 100 ETF

Cambria Tax Aware ETF

John Hancock Mid Cap Growth Fund Class I

John Hancock Mid Cap Growth Fund Class A

John Hancock Mid Cap Growth Fund Class NAV

John Hancock Variable Insurance Trust Mid Growth Trust Series Nav

Alger Small Cap Growth Fund Class C

Alger Small Cap Growth Fund Class B

Alger Small Cap Growth Fund Class Z

MFS New Discovery Value Fund Class B

MFS New Discovery Value Fund Class R1

MFS New Discovery Value Fund Class R4

MFS New Discovery Value Fund Class A

Tema Heart & Health ETF

Buffalo Small Cap Fund Institutional Class

The Hartford Small Cap Growth Fund Class C

The Hartford Small Cap Growth Fund Class R3

The Hartford Small Cap Growth Fund Class R4

The Hartford Small Cap Growth Fund Class R5

VALIC Company I Small Cap Growth Fund

Hartford Small Cap Growth HLS Fund Class IA

JPMorgan Mid Cap Growth Fund Class I

JPMorgan Mid Cap Growth Fund Class R6

JPMorgan Mid Cap Growth Fund Class R2

JPMorgan Mid Cap Growth Fund Class C

Calamos Convertible Equity Alternative ETF

AMG TimesSquare Mid Cap Growth Fund- Class Z

AMG TimesSquare Mid Cap Growth Fund Class I

OneAscent Enhanced Small and Mid Cap ETF

First Trust Nasdaq Pharmaceuticals ETF

Rydex Health Care Fund Class A

Rydex Health Care Fund Class C

Vanguard Explorer Fund Admiral Shares

Artisan Mid Cap Fund Institutional Class

Kennedy Capital ESG SMID Cap Fund

American Century Small Cap Growth Fund Class C

American Century Small Cap Growth Fund

American Century Small Cap Growth Fund Investor Class

American Century Small Cap Growth Fund R Class

MoA Mid Cap Value Fund

WisdomTree Efficient Long/Short US Equity Fund ETF

MFS Blended Research Small Cap Equity Fund Class A

MFS Blended Research Small Cap Equity Fund Class I

MFS Blended Research Small Cap Equity Fund Class R1

MFS Blended Research Small Cap Equity Fund Class R3

MFS Blended Research Small Cap Equity Fund Class R6

SMALLCAP World Fund Class 529-E

SMALLCAP World Fund Class 529-F1

SMALLCAP World Fund Class 529-F-2

SMALLCAP World Fund Class R-2E

SMALLCAP World Fund Inc Class R-3 Shares

SMALLCAP World Fund Inc Class R-5 Shares

SMALLCAP World Fund Class R5E

SMALLCAP World Fund Class C

SMALLCAP World Fund Class F2

Virtus Convertible & Income Fund II

John Hancock Variable Insurance Trust Small Stock Trust Series II

John Hancock Variable Insurance Trust Small Stock Trust Series I

Hartford Small Company HLS Fund Class IB

Voya Russell Mid Cap Growth Index Portfolio Initial

Voya Russell Mid Cap Growth Index Portfolio Class S

T. Rowe Price Diversified Mid-Cap Growth Fund Class I

Vanguard Small Cap Growth Index Fund admiral Class

VY T. Rowe Price Diversified Mid Cap Growth Portfolio Initial

VY T. Rowe Price Diversified Mid Cap Growth Portfolio S2

VY T. Rowe Price Diversified Mid Cap Growth Portfolio Class R6

iShares Russell Midcap Growth ETF

Invesco Dorsey Wright SmallCap Momentum ETF

Fidelity Flex Mid Cap Index Fund

BNY Mellon US Mid Cap Core Equity ETF

Calamos Global Total Return Fund

Schwab US Small-Cap ETF

Vanguard Market Neutral Fund Investor Shs