Mutual Funds Holding INSM

AlphaCentric Life Sciences and Healthcare Fund Class I

Fidelity Advisor Biotechnology Fund Class C

Fidelity Advisor Biotechnology Fund Class M

Eventide Healthcare & Life Sciences Fund Class A

Eventide Healthcare & Life Sciences Fund Class I

Franklin Biotechnology Discovery Fund Class A

Franklin Biotechnology Discovery Fund Class R6

Value Line Larger Companies Focused Fund Investor Class

Baron Health Care Fund Retail Class

Baron Health Care Fund Class R6

Victory RS Select Growth Fund Class C

Victory RS Select Growth Fund Class Y

Yorktown Small Cap Fund Class L

Nicholas Partners Small Cap Growth Fund Institutional Class

NYLI Fiera SMID Growth Fund Institutional Class

NYLI Fiera SMID Growth Fund Class C

Rydex Biotechnology Fund Class C

Rydex Biotechnology Fund Investor Class

Alger Small Cap Growth Portfolio Class I2

Global Endurance Portfolio - Class I

Global Endurance Portfolio - Class R6

Riverpark/Next Century Large Growth Fund Retail Class

AMG TimesSquare Mid Cap Growth Fund- Class N

Touchstone Mid Cap Growth Fund Class A

Touchstone Mid Cap Growth Fund Class Y

Touchstone Mid Cap Growth Fund Class C

JPMorgan Mid Cap Growth Fund Class I

JPMorgan Mid Cap Growth Fund Class R6

JPMorgan Mid Cap Growth Fund Class R2

JPMorgan Mid Cap Growth Fund Class C

Hood River New Opportunities Fund Retirement Class

Hood River New Opportunities Fund Investor Class

Allspring SMID Cap Growth Fund Administrator Class

Allspring SMID Cap Growth Fund Institutional Class

Columbia Acorn Trust Acorn Fund Class S

Columbia Acorn Trust Acorn Fund Institutional Class III

Columbia Acorn Trust Acorn Fund Class C

Loomis Sayles Small/Mid Cap Growth Fund Class N

Principal SmallCap Fund Class J

Principal SmallCap Fund Class R-5

Principal SmallCap Fund Class R6

DWS Small Cap Growth Fund Class C

DWS Small Cap Growth Fund Class S

Alger Small Cap Growth Fund Class C

Alger Small Cap Growth Fund Class B

Alger Small Cap Growth Fund Class Z

1290 Essex Small Cap Growth Fund Class I

William Blair Small-Mid Cap Growth Fund Class I

William Blair Small-Mid Cap Growth Fund Class N

John Hancock Variable Insurance Trust Health Sciences Trust Series Nav

T. Rowe Price Health Sciences Portfolio

T. Rowe Price Health Sciences Fund Investor Class

Baird Small/Mid Cap Growth Fund Institutional Class

AMG GW&K Small/Mid Cap Fund Class I

AMG GW&K Small/Mid Cap Fund Class Z

Invesco Health Care Fund Class A

Invesco Health Care Fund Class R

Invesco Health Care Fund Class R6

Columbia Select Large Cap Growth Fund Class Institutional 2

Columbia Select Large Cap Growth Fund Class S

Columbia Select Large Cap Growth Fund Class R

PGIM Jennison Mid-Cap Growth Fund Class A

PGIM Jennison Mid-Cap Growth Fund Class C

PGIM Jennison Mid-Cap Growth Fund Class Z

Victory Pioneer Select Mid Cap Growth Fund Class C

Victory Pioneer Select Mid Cap Growth Fund Class A

JPMorgan Large Cap Growth Fund Class R6

JPMorgan Large Cap Growth Fund Class R4

JPMorgan Large Cap Growth Fund Class R2

JPMorgan Large Cap Growth Fund Class C

Nomura Smid Cap Core Fund Class R6

Nomura Smid Cap Core Fund Class A

Nomura Smid Cap Core Fund Class Y

Nomura Mid Cap Growth Fund Class R6

Nomura Mid Cap Growth Fund Class A

Nomura Mid Cap Growth Fund Class Y

Victory RS Science and Technology Fund Class Y

Victory RS Science and Technology Fund Class A

PGIM Jennison Health Sciences Fund Class A

PGIM Jennison Health Sciences Fund Class Z

Voya MI Dynamic SMID Cap Fund Class R6

Voya MI Dynamic SMID Cap Fund Class C

Voya MI Dynamic SMID Cap Fund Class R

Fidelity Select Health Care Portfolio

Carillon Eagle Mid Cap Growth Fund Class C

Carillon Eagle Mid Cap Growth Fund Class R-6

ClearBridge Variable Small Cap Growth Portfolio Class II

Neuberger Berman Mid Cap Growth Fund Institutional Class

Neuberger Berman Mid Cap Growth Fund Investor Class

Neuberger Berman Mid Cap Growth Fund Class A

Neuberger Berman Mid Cap Growth Fund Class R6

Goldman Sachs Mid Cap Growth Fund Class A

Goldman Sachs Mid Cap Growth Fund Cl R

Goldman Sachs Mid Cap Growth Fund Investor Class

Goldman Sachs Mid Cap Growth Fund Class P Shares

JPMorgan Growth Advantage Fund Class I

JPMorgan Growth Advantage Fund Class R4

JPMorgan Growth Advantage Fund Class R6

JPMorgan Growth Advantage Fund Class A

Fidelity Advisor Health Care Fund Class M

Fidelity Advisor Health Care Fund Class I

Columbia Select Mid Cap Growth Fund Class A

Columbia Select Mid Cap Growth Fund Class I

Columbia Select Mid Cap Growth Fund Class I2

Goldman Sachs Small/Mid-Cap Growth Fund Class A

Goldman Sachs Small/Mid-Cap Growth Fund Class C

Goldman Sachs Small/Mid-Cap Growth Fund Class P

Goldman Sachs Small/Mid-Cap Growth Fund Class R6

Columbia Large Cap Growth Opportunity Fund Class Institutional 2

Columbia Large Cap Growth Opportunity Fund Institutional Class III

Columbia Large Cap Growth Opportunity Fund Class S

Bridge Builder Small/Mid Cap Growth Fund

Fidelity Mid Cap Growth Index Fund

Voya Russell Mid Cap Growth Index Portfolio Class S2

Value Line Capital Appreciation Fund Investor Class

T. Rowe Price Diversified Mid-Cap Growth Fund Investor Class

Invesco Summit Fund Class A

Invesco Summit Fund Class C

Invesco Summit Fund Class P

Invesco Summit Fund Class S

VY T. Rowe Price Diversified Mid Cap Growth Portfolio Class S

VY T. Rowe Price Diversified Mid Cap Growth Portfolio Advisor Class

Eventide Gilead Fund Class A

Eventide Gilead Fund Class N

The Hartford Small Company Fund Class Y

The Hartford Small Company Fund Class A

The Hartford Small Company Fund Class I

The Hartford Small Company Fund Class R6

The Hartford Small Company Fund Class R4

Lord Abbett Health Care Fund

Lord Abbett Health Care Fund Class I

Lord Abbett Health Care Fund Class F

Lord Abbett Health Care Fund Class R6

Brown Advisory Sustainable Small-Cap Core Fund Class Institutional

Putnam Small Cap Growth Fund Class A

Putnam Small Cap Growth Fund Class R6

Putnam Small Cap Growth Fund Class Y

Franklin Small - Mid Cap Growth Fund Class A

Franklin Small -Mid Cap Growth Fund Advisor Class

ClearBridge Small Cap Growth Fund Class IS

ClearBridge Small Cap Growth Fund Class R

ClearBridge Small Cap Growth Fund Class A

ClearBridge Small Cap Growth Fund Class C

Victory Science & Technology Fund Class A

Columbia Integrated Small Cap Growth Fund Class Institutional

Fidelity Growth Strategies Fund

Fidelity Growth Strategies Fund Class M

Fidelity Growth Strategies Fund Class I

Franklin Growth Opportunities Fund Class A

Franklin Growth Opportunities Fund Class R

Franklin Growth Opportunities Fund Advisor Class

Nomura Science and Technology Fund Class N

Lord Abbett Growth Opportunities Fund Class F

Lord Abbett Growth Opportunities Fund Class R3

Lord Abbett Growth Opportunities Fund Class R5

Lord Abbett Growth Opportunities Fund Class R2

Lord Abbett Growth Opportunities Fund Class C

Lord Abbett Growth Opportunities Fund Class F3

Nomura Science and Technology Fund Class R

Nomura Science and Technology Fund Class C

GuideStone Funds Growth Equity Fund Investor Class

John Hancock Variable Insurance Trust Small Stock Trust Series Nav

Vanguard Mid-Cap Growth Fund

Hartford Small Company HLS Fund Class IA

PACE Large Company Growth Equity Investments Class A

T. Rowe Price New Horizons Fund Investor Class

Nuveen Mid Cap Growth Opportunities Fund Class I

Nuveen Mid Cap Growth Opportunities Fund Class A

MoA Small Cap Growth Fund

Rydex Health Care Fund Class A

Rydex Health Care Fund Class C

Hood River Small Cap Growth Fund Institutional Class

Putnam Global Health Care Fund Class C

Putnam Global Health Care Fund Class R

VALIC Company I Mid Cap Strategic Growth Fund

American Century Focused Dynamic Growth Fund Class R

American Century Focused Dynamic Growth Fund

American Century Focused Dynamic Growth Fund Investor Class

Empower Large Cap Growth Fund Institutional Class

Emerald Insights Fund Class A