ETFs Holding BIIB

Fidelity Advisor Biotechnology Fund Class A

Fidelity Advisor Biotechnology Fund Class I

Fidelity Advisor Biotechnology Fund Class Z

Patient Opportunity Trust Class A

Patient Opportunity Trust Class FI

Patient Opportunity Trust Class R

Alger Mid Cap Focus Fund Class I

Alger Mid Cap Focus Fund Class A

Alger Mid Cap Focus Fund Class Y

iShares Biotechnology ETF

Vanguard PRIMECAP Fund Admiral Shares

Pacer US Small Cap Cash Cows ETF

Rydex Biotechnology Fund Class A

Rydex Biotechnology Fund Class H

PRIMECAP Odyssey Aggressive Growth Fund

Strategas Global Policy Opportunities ETF

AlphaCentric Life Sciences and Healthcare Fund Class A

AlphaCentric Life Sciences and Healthcare Fund Class I

Vanguard PRIMECAP Core Fund Investor Shs

Vanguard Capital Opportunity Fund Admiral Shares

JPMorgan Healthcare Leaders ETF

Cultivar ETF

Motley Fool Next Index ETF

VanEck Morningstar SMID Moat ETF

Causeway Global Value Fund Institutional Class

First Trust Health Care AlphaDEX Fund

Victory Pioneer Disciplined Value Fund Class A

Victory Pioneer Disciplined Value Fund Class R6

Motley Fool Value Factor ETF

Transamerica Mid Cap Value Opportunities Fund Class A

Transamerica Mid Cap Value Opportunities Fund Class R6

Transamerica Mid Cap Value Opportunities Fund Class R4

Transamerica Mid Cap Value Opportunities Fund Class I3

Vanguard Health Care Fund

Victory Pioneer Mid Cap Value Fund Class C

Victory Pioneer Mid Cap Value Fund Class R6

Victory Pioneer Core Equity Fund Class R6

Victory Pioneer Core Equity Fund Class A

State Street SPDR S&P Biotech ETF

Fidelity Select Biotechnology Portfolio

BlackRock Health Sciences Opportunity Investor A Class

BlackRock Health Sciences Opportunities Portfolio Institutional Class

BlackRock Health Sciences Opportunities Portfolio Class K

American Beacon Man Large Cap Value Fund A Class

American Beacon Man Large Cap Value Fund Investor Class

American Beacon Man Large Cap Value Fund R6 Class

The Hartford Healthcare Fund Class A

The Hartford Healthcare Fund Class C

The Hartford Healthcare Fund Cl R4

The Hartford Healthcare Fund Cl R5

The Hartford Healthcare Fund Class Y

Invesco S&P 500 Value with Momentum ETF

Biotechnology UltraSector ProFund

Brown Advisory Intermediate Income Fund Investor Shares

Fidelity Select Pharmaceuticals Portfolio

Fidelity Advisor Healthy Future Fund Class C

Fidelity Advisor Healthy Future Fund Class I

Impax Global Women's Leadership Fund Investor Class

Leuthold Select Industries ETF

DWS Health and Wellness Fund Class A

DWS Health and Wellness Fund Class Institutional

Transamerica Small/Mid Cap Value Fund Class A

Transamerica Small/Mid Cap Value Fund Class I2

Fidelity US Multifactor ETF

Alpha Blue Capital US Small-Mid Cap Dynamic ETF

Nomura Healthcare Fund Class A

Nomura Healthcare Fund Class R

S&P 500 Pure Value Fund Class C

Avantis US Mid Cap Value ETF

Wisdomtree BioRevolution Fund

MFS Blended Research Mid Cap Equity Fund Class B

MFS Blended Research Mid Cap Equity Fund Class I

MFS Blended Research Mid Cap Equity Fund Class R2

MFS Blended Research Mid Cap Equity Fund Class R4

MFS Blended Research Mid Cap Equity Fund Class R6

Portfolio Building Block World Pharma and Biotech Index ETF

Rydex Health Care Fund Class A

Rydex Health Care Fund Class C

First Trust S&P 500 Diversified Free Cash Flow ETF

JPMorgan Large Cap Value Fund Class R6

JPMorgan Large Cap Value Fund Class R2

JPMorgan Large Cap Value Fund Class R4

JPMorgan Large Cap Value Fund Class C

Convergence Long/Short Equity ETF

John Hancock Disciplined Value Mid Cap Fund Class I

John Hancock Disciplined Value Mid Cap Fund Class R6

John Hancock Disciplined Value Mid Cap Fund Class R2

LSV Disciplined Value ETF

Alger Dynamic Opportunities Fund Class Z

Leuthold Core Investment Fund Inst Cl

Alger Capital Appreciation Portfolio Class I2

AQR Style Premia Alternative Fund Class R6

BlackRock Health Sciences Trust

Alger Focus Equity Fund Class A

Alger Focus Equity Fund Class Y

Alger Focus Equity Fund Class Z

Fidelity Women's Leadership Fund Class A

Fidelity Women's Leadership Fund Class M

Fidelity Women's Leadership Fund

Fidelity Advisor Sustainable US Equity Fund

Fidelity Advisor Sustainable US Equity Fund Class C

Fidelity Advisor Sustainable US Equity Fund Class I

Vanguard Mid-Cap Value ETF

Alger Responsible Investing Fund Class I

Alger Spectra Fund Class C

Alger Spectra Fund Class Y

Alger Spectra Fund Class A

State Street Health Care Select Sector SPDR ETF

NAA Opportunity Fund Class A

NAA Opportunity Fund Institutional Class

Morgan Stanley Institutional Fund Advantage Portfolio Class R6

Morgan Stanley Institutional Fund Advantage Portfolio Class A

Morgan Stanley Institutional Fund Advantage Portfolio Class C

Vanguard Mid-Cap Value Index Fund Investor Shares

Fidelity Series Intrinsic Opportunities Fund

RockCreek Global Equality ETF

Alger Capital Appreciation Institutional Fund Class R

Alger Capital Appreciation Fund Class Z

Alger Capital Appreciation Institutional Fund Class I

MFS Mid Cap Value Fund Class B

MFS Mid Cap Value Fund Class I

MFS Mid Cap Value Fund Class A

MFS Mid Cap Value Fund Class R4

MFS Mid Cap Value Fund Class R1

Invesco S&P 500 Pure Value ETF

Optimum Small-Mid Cap Growth Fund Class C

Fidelity MSCI Health Care Index ETF

Vanguard Health Care ETF

AQR Alternative Risk Premia Fund Class R6

AQR Alternative Risk Premia Fund Class N

Invesco S&P 500 Enhanced Value ETF

DWS Enhanced Core Equity Fund Class I

DWS Enhanced Core Equity Fund Class R

DWS Enhanced Core Equity Fund Class R6

Empower T. Rowe Price Mid Cap Growth Fund Institutional Class

T. Rowe Price Institutional Mid-Cap Equity Growth Fund

T. Rowe Price Mid-Cap Growth Portfolio

T. Rowe Price Mid-Cap Growth Fund Investor Class

T. Rowe Price Mid-Cap Growth Fund-R Class

Fidelity Puritan K6 Fund Class K6

Fidelity Fund Class K

Health Care UltraSector ProFund Investor

BlackRock Advantage Large Cap Value V.I. Fund Class I

Direxion Daily Healthcare Bull 3X ETF

Fidelity Puritan Fund Class K

AQR LSE Fusion Fund Class I

AQR LSE Fusion Fund Class R6

Franklin US Large Cap Equity Fund Class I

VALIC Company I Mid Cap Value Fund

JPMorgan Research Market Neutral Fund Class A

JPMorgan Research Market Neutral Fund Class I

BlackRock Advantage Large Cap Value Fund Class C

BlackRock Advantage Large Cap Value Fund Class K

iShares MSCI USA Value Factor ETF

PGIM Quant Solutions Large-Cap Core Fund Class Z

PGIM Quant Solutions Large-Cap Core Fund Class C

WisdomTree US Multifactor Fund

MassMutual Mid Cap Growth Fund Class A

MassMutual Mid Cap Growth Fund Class R3

MassMutual Mid Cap Growth Fund Class I

MassMutual Mid Cap Growth Fund Administrative Class

iShares Russell Mid-cap Value ETF

BlackRock Advantage Large Cap Core V.I. Fund Class II

JPMorgan Diversified Return US Mid Cap Equity ETF

T. Rowe Price Equity Income Portfolio

Vanguard Mid-Cap Index Fund Admiral Shares

Vanguard Mid-Cap Index Fund Institutional

Humankind US Stock ETF

Schwab Health Care Fund

Stratified LargeCap Index ETF

Federated Hermes MDT Large Cap Value ETF

Calvert US Large Cap Value Responsible Index Fund Class I

Calvert US Large Cap Value Responsible Index Fund Class R6

Calvert US Mid Cap Core Responsible Index Class A

ProShares Large Cap Core Plus

John Hancock Variable Insurance Trust Equity Income Trust Series Nav

John Hancock Variable Insurance Trust Equity Income Trust Series II

T. Rowe Price Equity Income Fund Investor Class

AQR MS Fusion Fund Class N

T. Rowe Price Equity Income Fund Class I

T. Rowe Price Equity Income Fund Class Z