Verastem, Inc., a development-stage biopharmaceutical company, focuses on developing and commercializing drugs for the treatment of cancer in the United States. Its product candidates are Avutometinib, an orally available small molecule RAF/MEK clamp that inhibits the ras sarcoma RAF/MEK, ERK mitogen activated pathway kinase pathway which is involved in cell proliferation, migration, transformation, and survival of tumor cells; and Defactinib, an oral small molecule inhibitor of FAK and proline-rich tyrosine kinase for various solid tumors. The company is involved in clinical studies, including RAMP 301, a randomized global confirmatory trial to evaluate the combination of Avutometinib and Defactinib for the treatment of patients with recurrent low-grade serous ovarian cancer; RAMP 201, an adaptive two-part multicenter, parallel cohort, randomized open label trial to evaluate the efficacy and safety of Avutometinib and in combination with Defactinib; and FRAME, an investigation of Avutometinib and Defactinib in patients with KRAS mutant cancers and subsequent analyses; and RAMP 204 and 205. It has license agreements with Chugai Pharmaceutical Co., Ltd. for the development, commercialization, and manufacture of products containing Avutometinib; and Pfizer Inc. to research, develop, manufacture, and commercialize products containing Pfizer's inhibitors of FAK for therapeutic, diagnostic, and prophylactic uses in humans. In addition, it has a clinical collaboration agreement with Amgen, Inc. to evaluate the combination of Avutometinib with Amgen's KRAS-G12C inhibitor LUMAKRAS which in Phase 1/2 trial entitled RAMP 203; and a discovery and development collaboration with GenFleet Therapeutics to advance new programs targeting RAS pathway-driven cancers. Verastem, Inc. was incorporated in 2010 and is headquartered in Needham, Massachusetts.

Verastem Inc.

An update from Verastem ( ($VSTM) ) is now available. On November 13, 2025, Verastem, Inc. entered into an underwriting agreement with Jefferies LL...

Market Cap	$542.89M	P/E Ratio	N/A
52W High	$11.25	52W Low	$3.46
Div Yield	N/A	Payout Ratio	N/A
EPS Growth 3Y	9.4%	52W Position	79.0%
Overall Score	42	Value Score	40
Quality Score	42	Technical Score	45

EPS Current Est	$-3.24	EPS Next Est	$-2.17
EPS Growth Est	N/A	DPS Growth 3Y	N/A

	A	B	C	D
1	Symbol	Price	Change	Volume
2	VSTM	$9.61	+1.91%	1.73M
3
4
5

	A	B	C	D
1	Symbol	Price	Change	Vol
2	VSTM	$9.61	+1.9%	1.73M
3
4
5
6

VSTM

VSTM

Key Metrics Overview

Growth Analysis

Revenue (5Y)

EBITDA (5Y)

Get Verastem Inc. Data in Excel

Get Verastem Inc. Data in Excel