TMED vs VOO
T. Rowe Price Health Care ETF vs Vanguard S&P 500 ETF
Which is better, TMED or VOO?
Large Cap Value against Large Cap Blend.
VOO has a lower expense ratio. TMED led over 1Y and the full window. VOO is less concentrated, with 36.4% of the fund in its ten largest positions against 49.0%.
MarketXLS is not an investment adviser. This comparison is generated automatically from market data and is for information only. A Best mark means the better reading on that one measure, not a recommendation to buy.
Side-by-Side Comparison
| Metric | TMED | VOO |
|---|---|---|
| Expense Ratio | 0.44% | 0.03%Best |
| AUM | $33M | $997.4B |
| Dividend Yield | 0.46% | 1.04% |
| Holdings | 108 | 509 |
| YTD Return | +13.87%Best | +12.50% |
| 1Y Return | +29.28%Best | +17.58% |
| 3Y Return (annualized) | - | +21.27% |
| 5Y Return (annualized) | - | +12.95% |
| Volatility (annualized) | 15.4% | 11.9%Best |
| Max Drawdown | -11.1% | -8.9%Best |
| $10,000 over 1.2 years | $13,365Best | $12,725 |
| Top 10 Weight | 49.0% | 36.4%Best |
| Fund Family | T.Rowe Price | Vanguard (US) |
| Category | Equity | Equity |
| Style | Large Cap Value | Large Cap Blend |
| Inception | Jun 11, 2025 | Sep 7, 2010 |
Volatility and max drawdown, and the $10,000 over 1.2 years row, are measured over the window both funds cover: Jun 12, 2025 to Sep 11, 2026 (1.2 years).
TMED vs VOO growth
Month-end closes. Both lines start at 0% in the first month shown, so the gap between them is the difference in growth across that window. The full view covers the 1.2 years both funds cover.
TMED vs VOO Performance
T. Rowe Price Health Care ETF (TMED) is an ETF from T.Rowe Price and Vanguard S&P 500 ETF (VOO) is an ETF from Vanguard (US). Over the past year TMED returned +29.28% while VOO returned +17.58%. Year to date, TMED is up 13.87% versus a gain of 12.50% for VOO.
Past performance does not guarantee future results.
Risk: Volatility and Drawdowns
TMED has been the more volatile fund, with annualized monthly volatility of 15.4% compared with 11.9% for VOO. Lower volatility generally means a smoother ride, though it often comes with lower long-run returns.
The deepest peak-to-trough decline in our data was -11.1% for TMED and -8.9% for VOO. Drawdown depth is what each fund did in the worst stretch of the window measured above.
The two funds' monthly returns correlate at 0.41. They move together some of the time, and apart the rest.
Fees and Cost Over Time
TMED charges 0.44% per year while VOO charges 0.03%. On a $10,000 position that is $44 vs $3 annually, a gap of $41 per year that compounds over a long holding period. On income, TMED currently yields 0.46% against 1.04% for VOO.
Holdings Overlap
62.9% of TMED's money is in holdings VOO also owns. 4.2% of VOO's money is in holdings TMED also owns.
The two portfolios partly overlap.
24 positions in common, counted across the 97 positions we hold weights for in TMED and 505 in VOO, against full books of 108 and 509.
What only one of them owns
Our book lists 472 positions for VOO that do not appear in our book for TMED (95.3% of the fund), and 65 for TMED that do not appear in VOO (32.1%).
Some of those will be the same company recorded under a different code in one of the two books, so the real difference in what you would own is no larger than this and may be smaller. We do not name the individual positions here for that reason.
Top Shared Holdings
| Stock | Weight in TMED | Weight in VOO | Difference |
|---|---|---|---|
| LLYEli Lilly & Co. | 16.48% | 1.47% | 15.01% |
| UNHUnitedhealth Group Inc. | 5.74% | 0.59% | 5.15% |
| TMOThermo Fisher Scientific Inc | 4.37% | 0.29% | 4.08% |
| CORCencora, Inc. | 3.29% | 0.09% | 3.20% |
| GILDGilead Sciences Inc | 3.08% | 0.24% | 2.84% |
| DHRDanaher Corp. | 2.94% | 0.19% | 2.75% |
| PODDInsulet Corp | 2.98% | 0.02% | 2.96% |
| AAgilent Tech In 3.2 10/22 | 2.68% | 0.06% | 2.62% |
| SYKStryker Corp 3.375 11/25 | 2.37% | 0.17% | 2.20% |
| DXCMDexcom Inc. | 2.42% | 0.04% | 2.38% |
62.9% of TMED is already inside VOO.
You probably hold more than these two. Add the rest and see how much of the whole book is the same companies twice.
Free for up to 10 holdings. No account needed.
Frequently Asked Questions
Which is cheaper, TMED or VOO?
TMED has an expense ratio of 0.44% while VOO charges 0.03%. VOO is the cheaper option, by $41 a year on a $10,000 investment.
Which performed better, TMED or VOO?
Over the past year TMED returned +29.28% vs +17.58% for VOO, so TMED leads on 1-year performance. Over the longest common window we track (1 years), TMED annualized +27.34% vs +22.24% for VOO. Past performance does not guarantee future results. This is information, not a recommendation.
Which is riskier, TMED or VOO?
TMED has been the more volatile fund at 15.4% annualized versus 11.9% for VOO. Worst drawdown: TMED -11.1% vs VOO -8.9%.
Should I hold both TMED and VOO?
TMED and VOO have a monthly-return correlation of 0.41, so their returns are far enough apart for the mix to behave differently from either one alone. This is information, not a recommendation.
What is the holdings overlap between TMED and VOO?
62.9% of TMED's money is in holdings VOO also owns. 4.2% of VOO's is in holdings TMED also owns. They hold 24 positions in common, counted across the 97 positions we hold weights for in TMED and 505 in VOO.
Which pays a higher dividend, TMED or VOO?
TMED yields 0.46% while VOO yields 1.04%, so VOO currently pays the higher dividend yield.
Is VOO better than TMED?
VOO has a lower expense ratio. TMED led over 1Y and the full window. VOO is less concentrated, with 36.4% of the fund in its ten largest positions against 49.0%. Which one suits a particular account depends on what it is for. This is information, not a recommendation.