Olema Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of therapies for women's cancers. The company's lead product candidate is palazestrant, an estrogen receptor (ER) antagonist and a selective ER degrader, which is in Phase 3 clinical trial for the treatment of recurrent, locally advanced, or metastatic estrogen receptor-positive, human epidermal growth factor receptor 2-negative breast cancer; OPERA-01, the pivotal Phase 3 clinical trial of palazestrant as a monotherapy in second/third-line ER+/HER2- metastatic breast cancer; and palazestrant with CDK4/6 inhibitors palbociclib and ribociclib, a phosphatidylinositol 3 kinase alpha (PI3Ka) inhibitor alpelisib, and with an mTOR inhibitor everolimus that is in Phase 1/2 clinical trial for the treatment of recurrent, locally advanced, or metastatic estrogen receptor-positive human epidermal growth factor receptor 2-negative breast cancer. It also develops OP-3136, an orally-available small molecule that potently and selectively inhibits KAT6 for patients with ER+/HER2- metastatic breast cancer and other cancers which is in Phase 1 clinical trial. The company was formerly known as CombiThera, Inc. and changed its name to Olema Pharmaceuticals, Inc. in March 2009. Olema Pharmaceuticals, Inc. was incorporated in 2006 and is headquartered in San Francisco, California.

Olema Pharmaceuticals Inc.

Oppenheimer analyst Matthew Biegler reiterated a Buy rating on Olema Pharmaceuticals today and set a price target of $48.00. According to TipRanks,...

Oppenheimer Sticks to Their Buy Rating for Olema Pharmaceuticals (OLMA)

In a report released today, Sam Slutsky from LifeSci Capital maintained a Buy rating on Olema Pharmaceuticals, with a price target of $39.00. Accor...

LifeSci Capital Reaffirms Their Buy Rating on Olema Pharmaceuticals (OLMA)

Olema Pharmaceuticals ( ($OLMA) ) just unveiled an announcement. On November 18, 2025, Olema Pharmaceuticals announced a public offering of 10,000,...

Olema Pharmaceuticals Announces Public Stock Offering

Olema Pharmaceuticals ( ($OLMA) ) has issued an update. Olema Pharmaceuticals announced the termination of its ATM Prospectus, effective November 1...

Olema Pharmaceuticals Terminates ATM Prospectus

Tuesday’s biggest stock market stories include earnings reports, analyst updates, clinical trial results, and more.


Morning News Wrap-Up: Tuesday’s Biggest Stock Market Stories!

Olema Pharmaceuticals stock rallied on Tuesday alongside an update from rival drugmaker Roche.


	A	B	C	D
1	Symbol	Price	Change	Volume
2	OLMA	$33.05	+4.65%	3.62M
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	A	B	C	D
1	Symbol	Price	Change	Vol
2	OLMA	$33.05	+4.7%	3.62M
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