IBB vs VTI
iShares Biotechnology ETF vs Vanguard Morningstar Total Stock Market ETF
Which is better, IBB or VTI?
Mid Cap Blend against Large Cap Blend.
VTI has a lower expense ratio. IBB led over 1Y, VTI over 3Y, 5Y and the full window.
MarketXLS is not an investment adviser. This comparison is generated automatically from market data and is for information only. A Best mark means the better reading on that one measure, not a recommendation to buy.
Side-by-Side Comparison
| Metric | IBB | VTI |
|---|---|---|
| Expense Ratio | 0.44% | 0.03%Best |
| AUM | $10.5B | $666.9B |
| Dividend Yield | 0.22% | 1.07% |
| Holdings | 253 | 3,543 |
| YTD Return | +26.62%Best | +13.95% |
| 1Y Return | +52.63%Best | +21.44% |
| 3Y Return (annualized) | +18.95% | +21.10%Best |
| 5Y Return (annualized) | +4.26% | +11.77%Best |
| Volatility (annualized) | 21.3% | 15.3%Best |
| Max Drawdown | -62.9% | -56.6%Best |
| $10,000 over 5 years | $12,319 | $17,443Best |
| Fund Family | iShares by BlackRock (US) | Vanguard (US) |
| Category | Equity | Equity |
| Style | Mid Cap Blend | Large Cap Blend |
| Inception | Feb 5, 2001 | May 24, 2001 |
Not shown on this pair: Top 10 Weight.
Volatility and max drawdown are measured over the window both funds cover: May 31, 2001 to Sep 3, 2026 (25.3 years).
IBB vs VTI growth
Month-end closes. Both lines start at 0% in the first month shown, so the gap between them is the difference in growth across that window. The full view covers the 25.3 years both funds cover.
IBB vs VTI Performance
iShares Biotechnology ETF (IBB) is an ETF from iShares by BlackRock (US) and Vanguard Morningstar Total Stock Market ETF (VTI) is an ETF from Vanguard (US). Over the past year IBB returned +52.63% while VTI returned +21.44%. Year to date, IBB is up 26.62% versus a gain of 13.95% for VTI.
Over three years, IBB compounded at +18.95% per year against +21.10% for VTI; over five years the annualized figures are +4.26% and +11.77% respectively. Across the full 25-year window we track, VTI has the edge at +8.11% annualized vs +7.73%.
Past performance does not guarantee future results.
Risk: Volatility and Drawdowns
IBB has been the more volatile fund, with annualized monthly volatility of 21.3% compared with 15.3% for VTI. Lower volatility generally means a smoother ride, though it often comes with lower long-run returns.
The deepest peak-to-trough decline in our data was -62.9% for IBB and -56.6% for VTI. Drawdown depth is what each fund did in the worst stretch of the window measured above.
The two funds' monthly returns correlate at 0.65. They move together some of the time, and apart the rest.
Fees and Cost Over Time
IBB charges 0.44% per year while VTI charges 0.03%. On a $10,000 position that is $44 vs $3 annually, a gap of $41 per year that compounds over a long holding period. On income, IBB currently yields 0.22% against 1.07% for VTI.
Holdings Overlap
At least 79.3% of IBB's money is in holdings VTI also owns.
Stated as a floor: for VTI, our book for it covers 92.3% of that fund, so a holding it does not list is one we cannot count as shared. The real figure is this or higher.
Most of IBB is already inside VTI. Owning both mostly buys the same companies twice.
161 positions in common, counted across the 242 positions we hold weights for in IBB and 2,787 in VTI, against full books of 253 and 3,543.
Top Shared Holdings
| Stock | Weight in IBB | Weight in VTI | Difference |
|---|---|---|---|
| VRTXNvaesrtex Pharmaceuticals Inc | 8.38% | 0.17% | 8.21% |
| AMGNAmgen Inc. | 7.70% | 0.27% | 7.43% |
| GILDGilead Sciences | 6.82% | 0.22% | 6.60% |
| REGNRegeneron Pharmaceuticals, Inc. | 4.97% | 0.09% | 4.88% |
| ALNYAlnylam Pharmaceuticals Inc. | 3.16% | 0.06% | 3.10% |
| NTRANatera Inc | 2.94% | 0.05% | 2.89% |
| RVMDRevolution Medicines Inc | 2.74% | 0.05% | 2.69% |
| BIIBBiogen Inc. Com | 2.31% | 0.04% | 2.27% |
| MRNAModerna therapeutics | 2.25% | 0.03% | 2.22% |
| ILMNIllumina, Inc. | 2.22% | 0.03% | 2.19% |
79.3% of IBB is already inside VTI.
You probably hold more than these two. Add the rest and see how much of the whole book is the same companies twice.
Free for up to 10 holdings. No account needed.
Frequently Asked Questions
Which is cheaper, IBB or VTI?
IBB has an expense ratio of 0.44% while VTI charges 0.03%. VTI is the cheaper option, by $41 a year on a $10,000 investment.
Which performed better, IBB or VTI?
Over the past year IBB returned +52.63% vs +21.44% for VTI, so IBB leads on 1-year performance. Over the longest common window we track (25 years), IBB annualized +7.73% vs +8.11% for VTI. Past performance does not guarantee future results. This is information, not a recommendation.
Which is riskier, IBB or VTI?
IBB has been the more volatile fund at 21.3% annualized versus 15.3% for VTI. Worst drawdown: IBB -62.9% vs VTI -56.6%.
Should I hold both IBB and VTI?
IBB and VTI have a monthly-return correlation of 0.65, so their returns are far enough apart for the mix to behave differently from either one alone. This is information, not a recommendation.
What is the holdings overlap between IBB and VTI?
At least 79.3% of IBB's money is in holdings VTI also owns. Our book for VTI is partial, so the real figure is this or higher. They hold 161 positions in common, counted across the 242 positions we hold weights for in IBB and 2,787 in VTI.
Which pays a higher dividend, IBB or VTI?
IBB yields 0.22% while VTI yields 1.07%, so VTI currently pays the higher dividend yield.
Is VTI better than IBB?
VTI has a lower expense ratio. IBB led over 1Y, VTI over 3Y, 5Y and the full window. Which one suits a particular account depends on what it is for. This is information, not a recommendation.