PEPT vs VXUS
REX Peptide ETF vs Vanguard Total International Stock ETF
Which is better, PEPT or VXUS?
Mid Cap Growth against Large Cap Blend.
VXUS has a lower expense ratio.
MarketXLS is not an investment adviser. This comparison is generated automatically from market data and is for information only. A Best mark means the better reading on that one measure, not a recommendation to buy.
Side-by-Side Comparison
| Metric | PEPT | VXUS |
|---|---|---|
| Expense Ratio | 0.65% | 0.05%Best |
| AUM | $3M | $163.2B |
| Dividend Yield | 0.00% | 2.38% |
| Holdings | 33 | 9,293 |
| YTD Return | +8.13%Best | +6.50% |
| 1Y Return | - | +12.09% |
| 3Y Return (annualized) | - | +18.15% |
| 5Y Return (annualized) | - | +7.38% |
| Fund Family | REX Shares | Vanguard (US) |
| Category | Equity | Equity |
| Style | Mid Cap Growth | Large Cap Blend |
| Inception | Oct 14, 2026 | Jan 26, 2011 |
Not shown on this pair: Volatility (annualized), Max Drawdown, $10,000 over the window, Top 10 Weight.
PEPT vs VXUS growth
Month-end closes. Both lines start at 0% in the first month shown, so the gap between them is the difference in growth across that window. The full view is available from the range buttons; it is not the opening view here because over the whole period one of these two funds moves so much further than the other that its line would sit flat on the axis.
PEPT vs VXUS Performance
REX Peptide ETF (PEPT) is an ETF from REX Shares and Vanguard Total International Stock ETF (VXUS) is an ETF from Vanguard (US). Year to date, PEPT is up 8.13% versus a gain of 6.50% for VXUS.
Past performance does not guarantee future results.
Fees and Cost Over Time
PEPT charges 0.65% per year while VXUS charges 0.05%. On a $10,000 position that is $65 vs $5 annually, a gap of $60 per year that compounds over a long holding period. On income, PEPT currently yields 0.00% against 2.38% for VXUS.
Holdings Overlap
At least 15.1% of PEPT's money is in holdings VXUS also owns.
Stated as a floor: for VXUS, our book for it covers 89.2% of that fund, so a holding it does not list is one we cannot count as shared. The real figure is this or higher.
PEPT and VXUS share little of their money.
9 positions in common, counted across the 33 positions we hold weights for in PEPT and 8,463 in VXUS, against full books of 33 and 9,293.
Top Shared Holdings
| Stock | Weight in PEPT | Weight in VXUS | Difference |
|---|---|---|---|
| BANB:FFBachem Holding Ag | 3.85% | 0.01% | 3.84% |
| IPN:PAIpsen Sa | 2.90% | 0.01% | 2.89% |
| ZEAL:COZealand Pharma A/s | 2.68% | 0.01% | 2.67% |
| NEU:AUNeuren Pharmaceuticals Ltd. | 1.90% | 0.00% | 1.90% |
| CAMX:STCamurus Ab | 1.29% | 0.01% | 1.28% |
| 4587:JPPeptidream Inc | 0.82% | 0.00% | 0.82% |
| PPGN:SMPolypeptide Group Ag | 0.72% | 0.00% | 0.72% |
| YPSN:SMYpsomed Holding Ag | 0.59% | 0.00% | 0.59% |
| GUBRA:COGubra As | 0.37% | 0.00% | 0.37% |
You are not choosing between two funds in isolation.
Whichever of PEPT and VXUS you pick has to sit alongside everything else you own. Add the rest and see what the combination actually holds.
Free for up to 10 holdings. No account needed.
Frequently Asked Questions
Which is cheaper, PEPT or VXUS?
PEPT has an expense ratio of 0.65% while VXUS charges 0.05%. VXUS is the cheaper option, by $60 a year on a $10,000 investment.
What is the holdings overlap between PEPT and VXUS?
At least 15.1% of PEPT's money is in holdings VXUS also owns. Our book for VXUS is partial, so the real figure is this or higher. They hold 9 positions in common, counted across the 33 positions we hold weights for in PEPT and 8,463 in VXUS.
Which pays a higher dividend, PEPT or VXUS?
PEPT yields 0.00% while VXUS yields 2.38%, so VXUS currently pays the higher dividend yield.
Is VXUS better than PEPT?
VXUS has a lower expense ratio. Which one suits a particular account depends on what it is for. This is information, not a recommendation.