PEPT vs VOO
REX Peptide ETF vs Vanguard S&P 500 ETF
Which is better, PEPT or VOO?
Mid Cap Growth against Large Cap Blend.
VOO has a lower expense ratio. VOO is less concentrated, with 39.1% of the fund in its ten largest positions against 71.4%.
MarketXLS is not an investment adviser. This comparison is generated automatically from market data and is for information only. A Best mark means the better reading on that one measure, not a recommendation to buy.
Side-by-Side Comparison
| Metric | PEPT | VOO |
|---|---|---|
| Expense Ratio | 0.65% | 0.03%Best |
| AUM | $3M | $1.0T |
| Dividend Yield | 0.00% | 1.05% |
| Holdings | 33 | 519 |
| YTD Return | +8.13% | +8.52%Best |
| 1Y Return | - | +10.96% |
| 3Y Return (annualized) | - | +20.51% |
| 5Y Return (annualized) | - | +10.97% |
| Top 10 Weight | 71.4% | 39.1%Best |
| Fund Family | REX Shares | Vanguard (US) |
| Category | Equity | Equity |
| Style | Mid Cap Growth | Large Cap Blend |
| Inception | Oct 14, 2026 | Sep 7, 2010 |
Not shown on this pair: Volatility (annualized), Max Drawdown, $10,000 over the window.
PEPT vs VOO growth
Month-end closes. Both lines start at 0% in the first month shown, so the gap between them is the difference in growth across that window. The full view is available from the range buttons; it is not the opening view here because over the whole period one of these two funds moves so much further than the other that its line would sit flat on the axis.
PEPT vs VOO Performance
REX Peptide ETF (PEPT) is an ETF from REX Shares and Vanguard S&P 500 ETF (VOO) is an ETF from Vanguard (US). Year to date, PEPT is up 8.13% versus a gain of 8.52% for VOO.
Past performance does not guarantee future results.
Fees and Cost Over Time
PEPT charges 0.65% per year while VOO charges 0.03%. On a $10,000 position that is $65 vs $3 annually, a gap of $62 per year that compounds over a long holding period. On income, PEPT currently yields 0.00% against 1.05% for VOO.
Holdings Overlap
21.9% of PEPT's money is in holdings VOO also owns. 1.4% of VOO's money is in holdings PEPT also owns.
PEPT and VOO share little of their money.
2 positions in common, counted across the 33 positions we hold weights for in PEPT and 506 in VOO, against full books of 33 and 519.
What only one of them owns
Our book lists 499 positions for VOO that do not appear in our book for PEPT (98.5% of the fund), and 16 for PEPT that do not appear in VOO (33.9%).
Some of those will be the same company recorded under a different code in one of the two books, so the real difference in what you would own is no larger than this and may be smaller. We do not name the individual positions here for that reason.
21.9% of PEPT is already inside VOO.
You probably hold more than these two. Add the rest and see how much of the whole book is the same companies twice.
Free for up to 10 holdings. No account needed.
Frequently Asked Questions
Which is cheaper, PEPT or VOO?
PEPT has an expense ratio of 0.65% while VOO charges 0.03%. VOO is the cheaper option, by $62 a year on a $10,000 investment.
What is the holdings overlap between PEPT and VOO?
21.9% of PEPT's money is in holdings VOO also owns. 1.4% of VOO's is in holdings PEPT also owns. They hold 2 positions in common, counted across the 33 positions we hold weights for in PEPT and 506 in VOO.
Which pays a higher dividend, PEPT or VOO?
PEPT yields 0.00% while VOO yields 1.05%, so VOO currently pays the higher dividend yield.
Is VOO better than PEPT?
VOO has a lower expense ratio. VOO is less concentrated, with 39.1% of the fund in its ten largest positions against 71.4%. Which one suits a particular account depends on what it is for. This is information, not a recommendation.