QQQ vs TDNA
Invesco QQQ Trust, Series 1 vs T. Rowe Price Biotech ETF
Which is better, QQQ or TDNA?
Large Cap Growth against Small Cap Growth.
QQQ has a lower expense ratio. TDNA is less concentrated, with 28.7% of the fund in its ten largest positions against 46.9%.
MarketXLS is not an investment adviser. This comparison is generated automatically from market data and is for information only. A Best mark means the better reading on that one measure, not a recommendation to buy.
Side-by-Side Comparison
| Metric | QQQ | TDNA |
|---|---|---|
| Expense Ratio | 0.18%Best | 0.55% |
| AUM | $437.3B | $11M |
| Dividend Yield | 0.43% | 0.00% |
| Holdings | 208 | 174 |
| YTD Return | +12.98%Best | +0.43% |
| 1Y Return | +11.59% | - |
| 3Y Return (annualized) | +23.05% | - |
| 5Y Return (annualized) | +12.74% | - |
| Top 10 Weight | 46.9% | 28.7%Best |
| Fund Family | Invesco (US) | T.Rowe Price |
| Category | Equity | Equity |
| Style | Large Cap Growth | Small Cap Growth |
| Inception | Mar 10, 1999 | Sep 16, 2026 |
Not shown on this pair: Volatility (annualized), Max Drawdown, $10,000 over the window.
QQQ vs TDNA growth
Month-end closes. Both lines start at 0% in the first month shown, so the gap between them is the difference in growth across that window. The full view is available from the range buttons; it is not the opening view here because over the whole period one of these two funds moves so much further than the other that its line would sit flat on the axis.
QQQ vs TDNA Performance
Invesco QQQ Trust, Series 1 (QQQ) is an ETF from Invesco (US) and T. Rowe Price Biotech ETF (TDNA) is an ETF from T.Rowe Price. Year to date, QQQ is up 12.98% versus a gain of 0.43% for TDNA.
Past performance does not guarantee future results.
Fees and Cost Over Time
QQQ charges 0.18% per year while TDNA charges 0.55%. On a $10,000 position that is $18 vs $55 annually, a gap of $37 per year that compounds over a long holding period. On income, QQQ currently yields 0.43% against 0.00% for TDNA.
Holdings Overlap
3.3% of QQQ's money is in holdings TDNA also owns. 9.5% of TDNA's money is in holdings QQQ also owns.
TDNA and QQQ share little of their money.
6 positions in common, counted across the 101 positions we hold weights for in QQQ and 85 in TDNA, against full books of 208 and 174.
What only one of them owns
Our book lists 73 positions for TDNA that do not appear in our book for QQQ (79.7% of the fund), and 88 for QQQ that do not appear in TDNA (94.0%).
Some of those will be the same company recorded under a different code in one of the two books, so the real difference in what you would own is no larger than this and may be smaller. We do not name the individual positions here for that reason.
You are not choosing between two funds in isolation.
Whichever of QQQ and TDNA you pick has to sit alongside everything else you own. Add the rest and see what the combination actually holds.
Free for up to 10 holdings. No account needed.
Frequently Asked Questions
Which is cheaper, QQQ or TDNA?
QQQ has an expense ratio of 0.18% while TDNA charges 0.55%. QQQ is the cheaper option, by $37 a year on a $10,000 investment.
What is the holdings overlap between QQQ and TDNA?
9.5% of TDNA's money is in holdings QQQ also owns. 9.5% of TDNA's is in holdings QQQ also owns. They hold 6 positions in common, counted across the 101 positions we hold weights for in QQQ and 85 in TDNA.
Which pays a higher dividend, QQQ or TDNA?
QQQ yields 0.43% while TDNA yields 0.00%, so QQQ currently pays the higher dividend yield.
Is TDNA better than QQQ?
QQQ has a lower expense ratio. TDNA is less concentrated, with 28.7% of the fund in its ten largest positions against 46.9%. Which one suits a particular account depends on what it is for. This is information, not a recommendation.