SBIO vs VTI
ALPS Medical Breakthroughs ETF vs Vanguard Morningstar Total Stock Market ETF
Which is better, SBIO or VTI?
Small Cap Growth against Large Cap Blend.
VTI has a lower expense ratio. SBIO led over 1Y and 3Y, VTI over 5Y and the full window.
MarketXLS is not an investment adviser. This comparison is generated automatically from market data and is for information only. A Best mark means the better reading on that one measure, not a recommendation to buy.
Side-by-Side Comparison
| Metric | SBIO | VTI |
|---|---|---|
| Expense Ratio | 0.50% | 0.03%Best |
| AUM | $241M | $666.9B |
| Dividend Yield | 0.00% | 1.07% |
| Holdings | 107 | 3,543 |
| YTD Return | +34.19%Best | +13.95% |
| 1Y Return | +86.13%Best | +21.44% |
| 3Y Return (annualized) | +32.83%Best | +21.10% |
| 5Y Return (annualized) | +8.10% | +11.77%Best |
| Volatility (annualized) | 29.5% | 15.4%Best |
| Max Drawdown | -63.1% | -35.0%Best |
| $10,000 over 5 years | $14,761 | $17,443Best |
| Fund Family | ALPS Advisors | Vanguard (US) |
| Category | Equity | Equity |
| Style | Small Cap Growth | Large Cap Blend |
| Inception | Dec 30, 2014 | May 24, 2001 |
Not shown on this pair: Top 10 Weight.
Volatility and max drawdown are measured over the window both funds cover: Dec 31, 2014 to Sep 3, 2026 (11.7 years).
SBIO vs VTI growth
Month-end closes. Both lines start at 0% in the first month shown, so the gap between them is the difference in growth across that window. The full view covers the 11.7 years both funds cover.
SBIO vs VTI Performance
ALPS Medical Breakthroughs ETF (SBIO) is an ETF from ALPS Advisors and Vanguard Morningstar Total Stock Market ETF (VTI) is an ETF from Vanguard (US). Over the past year SBIO returned +86.13% while VTI returned +21.44%. Year to date, SBIO is up 34.19% versus a gain of 13.95% for VTI.
Over three years, SBIO compounded at +32.83% per year against +21.10% for VTI; over five years the annualized figures are +8.10% and +11.77% respectively. Across the full 12-year window we track, VTI has the edge at +12.31% annualized vs +9.69%.
Past performance does not guarantee future results.
Risk: Volatility and Drawdowns
SBIO has been the more volatile fund, with annualized monthly volatility of 29.5% compared with 15.4% for VTI. Lower volatility generally means a smoother ride, though it often comes with lower long-run returns.
The deepest peak-to-trough decline in our data was -63.1% for SBIO and -35.0% for VTI. Drawdown depth is what each fund did in the worst stretch of the window measured above.
The two funds' monthly returns correlate at 0.55. They move together some of the time, and apart the rest.
Fees and Cost Over Time
SBIO charges 0.50% per year while VTI charges 0.03%. On a $10,000 position that is $50 vs $3 annually, a gap of $47 per year that compounds over a long holding period. On income, SBIO currently yields 0.00% against 1.07% for VTI.
Holdings Overlap
At least 64.6% of SBIO's money is in holdings VTI also owns.
Stated as a floor: for VTI, our book for it covers 92.3% of that fund, so a holding it does not list is one we cannot count as shared. The real figure is this or higher.
The two portfolios partly overlap.
67 positions in common, counted across the 104 positions we hold weights for in SBIO and 2,787 in VTI, against full books of 107 and 3,543.
Top Shared Holdings
| Stock | Weight in SBIO | Weight in VTI | Difference |
|---|---|---|---|
| CRNXCrinetics Pharmaceuticals Inc Com | 4.55% | 0.00% | 4.55% |
| APGEApogee Therapeutics Inc | 4.24% | 0.01% | 4.23% |
| CGONCg Oncology Inc | 3.37% | 0.00% | 3.37% |
| TVTXTravere Therapeutics Inc | 2.94% | 0.00% | 2.94% |
| EWTXEdgewise Therapeutics Inc. | 2.42% | 0.00% | 2.42% |
| RLAYRelay Therapeutics Inc | 2.20% | 0.00% | 2.20% |
| DYNDyne Therapeutics Inc | 2.17% | 0.00% | 2.17% |
| DNLIDenali Therapeutics Inc | 1.97% | 0.00% | 1.97% |
| CLDXCelldex Therapeutics Inc | 1.68% | 0.00% | 1.68% |
| MBXMbx Biosciences Inc | 1.66% | 0.00% | 1.66% |
64.6% of SBIO is already inside VTI.
You probably hold more than these two. Add the rest and see how much of the whole book is the same companies twice.
Free for up to 10 holdings. No account needed.
Frequently Asked Questions
Which is cheaper, SBIO or VTI?
SBIO has an expense ratio of 0.50% while VTI charges 0.03%. VTI is the cheaper option, by $47 a year on a $10,000 investment.
Which performed better, SBIO or VTI?
Over the past year SBIO returned +86.13% vs +21.44% for VTI, so SBIO leads on 1-year performance. Over the longest common window we track (12 years), SBIO annualized +9.69% vs +12.31% for VTI. Past performance does not guarantee future results. This is information, not a recommendation.
Which is riskier, SBIO or VTI?
SBIO has been the more volatile fund at 29.5% annualized versus 15.4% for VTI. Worst drawdown: SBIO -63.1% vs VTI -35.0%.
Should I hold both SBIO and VTI?
SBIO and VTI have a monthly-return correlation of 0.55, so their returns are far enough apart for the mix to behave differently from either one alone. This is information, not a recommendation.
What is the holdings overlap between SBIO and VTI?
At least 64.6% of SBIO's money is in holdings VTI also owns. Our book for VTI is partial, so the real figure is this or higher. They hold 67 positions in common, counted across the 104 positions we hold weights for in SBIO and 2,787 in VTI.
Which pays a higher dividend, SBIO or VTI?
SBIO yields 0.00% while VTI yields 1.07%, so VTI currently pays the higher dividend yield.
Is VTI better than SBIO?
VTI has a lower expense ratio. SBIO led over 1Y and 3Y, VTI over 5Y and the full window. Which one suits a particular account depends on what it is for. This is information, not a recommendation.