SBIO vs VXUS
SBIO vs VXUS
ALPS Medical Breakthroughs ETF vs Vanguard Total International Stock ETF
Quick Verdict
VXUS has a lower expense ratio. SBIO delivered stronger 1-year returns. VXUS offers more diversification with 7861 holdings.
Side-by-Side Comparison
| Metric | SBIO | VXUS | Winner |
|---|---|---|---|
| Expense Ratio | 0.50% | 0.05% | |
| AUM | $202M | $156.5B | |
| Dividend Yield | 4.05% | 2.60% | |
| Holdings | 87 | 8,747 | |
| YTD Return | +34.80% | +14.57% | |
| 1Y Return | +106.24% | +27.82% | |
| 3Y Return (annualized) | +32.77% | +19.27% | |
| 5Y Return (annualized) | +9.56% | +9.28% | |
| Volatility (annualized) | 29.6% | 15.1% | |
| Max Drawdown | -63.1% | -39.9% | |
| Fund Family | ALPS Advisors | Vanguard (US) | |
| Category | Equity | Equity | |
| Inception | Dec 30, 2014 | Jan 26, 2011 |
SBIO vs VXUS Performance
ALPS Medical Breakthroughs ETF (SBIO) is a ETF from ALPS Advisors and Vanguard Total International Stock ETF (VXUS) is a ETF from Vanguard (US). Over the past year SBIO returned +106.24% while VXUS returned +27.82%. Year to date, SBIO is up 34.80% versus a gain of 14.57% for VXUS.
Over three years, SBIO compounded at +32.77% per year against +19.27% for VXUS; over five years the annualized figures are +9.56% and +9.28% respectively. Across the full 12-year window we track, SBIO has the edge at +9.80% annualized vs +4.86%. Past performance does not guarantee future results.
Risk: Volatility and Drawdowns
SBIO has been the more volatile fund, with annualized monthly volatility of 29.6% compared with 15.1% for VXUS. Lower volatility generally means a smoother ride, though it often comes with lower long-run returns.
The deepest peak-to-trough decline in our data was -63.1% for SBIO and -39.9% for VXUS. Drawdown depth is worth weighing if you expect to sell during market stress rather than ride it out.
The two funds' monthly returns correlate at 0.47. They move independently enough that combining them can meaningfully diversify a portfolio.
Fees and Cost Over Time
SBIO charges 0.50% per year while VXUS charges 0.05%. On a $10,000 position that is $50 vs $5 annually, a gap of $45 per year that compounds over a long holding period. On income, SBIO currently yields 4.05% against 2.60% for VXUS.
Holdings Overlap
SBIO and VXUS share 3 holdings out of 7963 unique holdings combined, representing a 0.0% weight overlap.
Moderate overlap means holding both could provide meaningful diversification benefits.
Frequently Asked Questions
Which is cheaper, SBIO or VXUS?
SBIO has an expense ratio of 0.50% while VXUS charges 0.05%. VXUS is the cheaper option. On a $10,000 investment, that is $45 per year of difference.
Which performed better, SBIO or VXUS?
Over the past year SBIO returned +106.24% vs +27.82% for VXUS, so SBIO leads on 1-year performance. Over the longest common window we track (12 years), SBIO annualized +9.80% vs +4.86% for VXUS. Past performance does not guarantee future results.
Which is riskier, SBIO or VXUS?
SBIO has been the more volatile fund at 29.6% annualized versus 15.1% for VXUS. Worst drawdown: SBIO -63.1% vs VXUS -39.9%.
Should I hold both SBIO and VXUS?
SBIO and VXUS have a monthly-return correlation of 0.47, so combining them can provide real diversification depending on your allocation goals.
What is the holdings overlap between SBIO and VXUS?
SBIO and VXUS share 3 common holdings with a 0.0% weight overlap. Combined, they hold 7963 unique securities.
Which pays a higher dividend, SBIO or VXUS?
SBIO yields 4.05% while VXUS yields 2.60%, so SBIO currently pays the higher dividend yield.
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