SBIO ETF

Fund Essentials - as of Jun 30, 2026

Net Assets
$221M
Expense Ratio
0.50%
Dividend Yield (Current)
-
Holdings
107
Inception Date
Dec 30, 2014
Fund Family
ALPS Advisors
Investment Style
PRO
Asset Class
PRO
Legal Structure
PRO
Dividend Frequency
Annually
SEC 30-Day Yield
PRO

Performance

YTD+24.18%
1 Year+94.10%
3 Year+27.12%
5 Year+8.34%
10 Year+10.63%

Asset Allocation

Stocks: 99.97%
Cash: 0.03%

Top Holdings

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TickerNameWeight
CRNXCrinetics Pharmaceuticals Inc Com4.74%
APGEApogee Therapeutics Inc4.47%
XENEXenon Pharmaceuticals Inc. Common Shares3.40%
CGONCg Oncology Inc3.29%
DNTHDianthus Therapeutics Inc3.05%
Top 10 Concentration: 32.15%Report Date: Jun 30, 2026
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Dividend Summary

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Frequency
Annually
Latest Distribution
$1.17
Dec 19, 2024

Peer Comparison

Benchmark
PRO
Peer outperformance: PRO
Category rank: PRO
This ETF
PRO
Peer Avg
PRO
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SBIO ETF Overview

SBIO ETF (ALPS Medical Breakthroughs ETF) is managed by ALPS Advisors with $220.6M in net assets. SBIO expense ratio is 0.50%, holding 107 positions across sectors including Health Care. Inception date: 2014-12-30.

SBIO performance shows a YTD return of 24.18%. The 1-year return is 94.10% and the 5-year return is 8.34%.

SBIO top holdings include Crinetics Pharmaceuticals Inc Com (4.7%), Apogee Therapeutics Inc (4.5%), Xenon Pharmaceuticals Inc. Common Shares (3.4%), Cg Oncology Inc (3.3%), Dianthus Therapeutics Inc (3.0%). Go to all SBIO holdings, SBIO sectors, or SBIO dividends.

SBIO can be compared against other funds. Use SBIO overlap to find shared positions, or SBIO vs another fund for a side-by-side view. SBIO alternatives are available via the screener, along with tax-loss harvesting opportunities.

1 Month
-1.64%
YTD
+24.18%
1 Year
+94.10%
3 Year
+27.12%

Top 10 Holdings (32.2% of portfolio)

#TickerNameSectorWeight
1CRNXCrinetics Pharmaceuticals Inc ComHealth Care4.74%
2APGEApogee Therapeutics IncHealth Care4.47%
3XENEXenon Pharmaceuticals Inc. Common SharesHealth Care3.40%
4CGONCg Oncology IncHealth Care3.29%
5DNTHDianthus Therapeutics IncHealth Care3.05%
6ORKAOruka Therapeutics Inc OrkaHealth Care2.99%
7TVTXTravere Therapeutics IncHealth Care2.87%
8DFTX:CADefinium Therapeutics, Inc. Common SharesUnknown2.53%
9MANEVeradermics IncUnknown2.45%
10EWTXEdgewise Therapeutics Inc.Health Care2.36%