IDNA vs VOO
iShares Genomics Immunology and Healthcare ETF vs Vanguard S&P 500 ETF
Which is better, IDNA or VOO?
Mid Cap Growth against Large Cap Blend.
VOO has a lower expense ratio. IDNA led over 1Y and 3Y, VOO over 5Y and the full window. VOO is less concentrated, with 36.4% of the fund in its ten largest positions against 43.5%.
MarketXLS is not an investment adviser. This comparison is generated automatically from market data and is for information only. A Best mark means the better reading on that one measure, not a recommendation to buy.
Side-by-Side Comparison
| Metric | IDNA | VOO |
|---|---|---|
| Expense Ratio | 0.47% | 0.03%Best |
| AUM | $257M | $997.4B |
| Dividend Yield | 0.86% | 1.08% |
| Holdings | 62 | 509 |
| YTD Return | +52.32%Best | +13.37% |
| 1Y Return | +78.00%Best | +20.08% |
| 3Y Return (annualized) | +22.29%Best | +21.29% |
| 5Y Return (annualized) | -5.36% | +12.89%Best |
| Volatility (annualized) | 26.0% | 16.4%Best |
| Max Drawdown | -68.3% | -34.3%Best |
| $10,000 over 5 years | $7,592 | $18,335Best |
| Top 10 Weight | 43.5% | 36.4%Best |
| Fund Family | iShares by BlackRock (US) | Vanguard (US) |
| Category | Equity | Equity |
| Style | Mid Cap Growth | Large Cap Blend |
| Inception | Jun 11, 2019 | Sep 7, 2010 |
Volatility and max drawdown are measured over the window both funds cover: Jun 13, 2019 to Sep 4, 2026 (7.2 years).
IDNA vs VOO growth
Month-end closes. Both lines start at 0% in the first month shown, so the gap between them is the difference in growth across that window. The full view covers the 7.2 years both funds cover.
IDNA vs VOO Performance
iShares Genomics Immunology and Healthcare ETF (IDNA) is an ETF from iShares by BlackRock (US) and Vanguard S&P 500 ETF (VOO) is an ETF from Vanguard (US). Over the past year IDNA returned +78.00% while VOO returned +20.08%. Year to date, IDNA is up 52.32% versus a gain of 13.37% for VOO.
Over three years, IDNA compounded at +22.29% per year against +21.29% for VOO; over five years the annualized figures are -5.36% and +12.89% respectively. Across the full 7-year window we track, VOO has the edge at +15.74% annualized vs +7.40%.
Past performance does not guarantee future results.
Risk: Volatility and Drawdowns
IDNA has been the more volatile fund, with annualized monthly volatility of 26.0% compared with 16.4% for VOO. Lower volatility generally means a smoother ride, though it often comes with lower long-run returns.
The deepest peak-to-trough decline in our data was -68.3% for IDNA and -34.3% for VOO. Drawdown depth is what each fund did in the worst stretch of the window measured above.
The two funds' monthly returns correlate at 0.57. They move together some of the time, and apart the rest.
Fees and Cost Over Time
IDNA charges 0.47% per year while VOO charges 0.03%. On a $10,000 position that is $47 vs $3 annually, a gap of $44 per year that compounds over a long holding period. On income, IDNA currently yields 0.86% against 1.08% for VOO.
Holdings Overlap
24.0% of IDNA's money is in holdings VOO also owns. 1.1% of VOO's money is in holdings IDNA also owns.
IDNA and VOO share little of their money.
7 positions in common, counted across the 50 positions we hold weights for in IDNA and 505 in VOO, against full books of 62 and 509.
What only one of them owns
Our book lists 490 positions for VOO that do not appear in our book for IDNA (98.3% of the fund), and 26 for IDNA that do not appear in VOO (40.6%).
Some of those will be the same company recorded under a different code in one of the two books, so the real difference in what you would own is no larger than this and may be smaller. We do not name the individual positions here for that reason.
Top Shared Holdings
| Stock | Weight in IDNA | Weight in VOO | Difference |
|---|---|---|---|
| REGNRegeneron Pharmaceuticals, Inc. | 4.26% | 0.10% | 4.16% |
| MRKMerck & Company Inc | 3.74% | 0.49% | 3.25% |
| MRNAModerna therapeutics | 4.18% | 0.04% | 4.14% |
| INCYIncyte Corp. | 4.12% | 0.03% | 4.09% |
| VRTXNvaesrtex Pharmaceuticals Inc | 3.82% | 0.20% | 3.62% |
| ROPRoper Technologies Inc. | 3.86% | 0.05% | 3.81% |
| GILDGilead Sciences Inc | 0.00% | 0.24% | 0.24% |
24.0% of IDNA is already inside VOO.
You probably hold more than these two. Add the rest and see how much of the whole book is the same companies twice.
Free for up to 10 holdings. No account needed.
Frequently Asked Questions
Which is cheaper, IDNA or VOO?
IDNA has an expense ratio of 0.47% while VOO charges 0.03%. VOO is the cheaper option, by $44 a year on a $10,000 investment.
Which performed better, IDNA or VOO?
Over the past year IDNA returned +78.00% vs +20.08% for VOO, so IDNA leads on 1-year performance. Over the longest common window we track (7 years), IDNA annualized +7.40% vs +15.74% for VOO. Past performance does not guarantee future results. This is information, not a recommendation.
Which is riskier, IDNA or VOO?
IDNA has been the more volatile fund at 26.0% annualized versus 16.4% for VOO. Worst drawdown: IDNA -68.3% vs VOO -34.3%.
Should I hold both IDNA and VOO?
IDNA and VOO have a monthly-return correlation of 0.57, so their returns are far enough apart for the mix to behave differently from either one alone. This is information, not a recommendation.
What is the holdings overlap between IDNA and VOO?
24.0% of IDNA's money is in holdings VOO also owns. 1.1% of VOO's is in holdings IDNA also owns. They hold 7 positions in common, counted across the 50 positions we hold weights for in IDNA and 505 in VOO.
Which pays a higher dividend, IDNA or VOO?
IDNA yields 0.86% while VOO yields 1.08%, so VOO currently pays the higher dividend yield.
Is VOO better than IDNA?
VOO has a lower expense ratio. IDNA led over 1Y and 3Y, VOO over 5Y and the full window. VOO is less concentrated, with 36.4% of the fund in its ten largest positions against 43.5%. Which one suits a particular account depends on what it is for. This is information, not a recommendation.