IDNA vs VOO
iShares Genomics Immunology and Healthcare ETF vs Vanguard S&P 500 ETF
Quick Verdict
VOO has a lower expense ratio. IDNA delivered stronger 1-year returns. VOO offers more diversification with 505 holdings.
Side-by-Side Comparison
| Metric | IDNA | VOO | Winner |
|---|---|---|---|
| Expense Ratio | 0.47% | 0.03% | |
| AUM | $190M | $979.0B | |
| Dividend Yield | 0.83% | 1.09% | |
| Holdings | 62 | 509 | |
| YTD Return | +35.66% | +13.72% | |
| 1Y Return | +65.26% | +21.63% | |
| 3Y Return (annualized) | +18.26% | +21.55% | |
| 5Y Return (annualized) | -6.91% | +13.26% | |
| Volatility (annualized) | 25.2% | 14.1% | |
| Max Drawdown | -68.3% | -34.3% | |
| Fund Family | iShares by BlackRock (US) | Vanguard (US) | |
| Category | Equity | Equity | |
| Inception | Jun 11, 2019 | Sep 7, 2010 |
IDNA vs VOO Performance
iShares Genomics Immunology and Healthcare ETF (IDNA) is a ETF from iShares by BlackRock (US) and Vanguard S&P 500 ETF (VOO) is a ETF from Vanguard (US). Over the past year IDNA returned +65.26% while VOO returned +21.63%. Year to date, IDNA is up 35.66% versus a gain of 13.72% for VOO.
Over three years, IDNA compounded at +18.26% per year against +21.55% for VOO; over five years the annualized figures are -6.91% and +13.26% respectively. Across the full 7-year window we track, VOO has the edge at +13.56% annualized vs +5.75%. Past performance does not guarantee future results.
Risk: Volatility and Drawdowns
IDNA has been the more volatile fund, with annualized monthly volatility of 25.2% compared with 14.1% for VOO. Lower volatility generally means a smoother ride, though it often comes with lower long-run returns.
The deepest peak-to-trough decline in our data was -68.3% for IDNA and -34.3% for VOO. Drawdown depth is worth weighing if you expect to sell during market stress rather than ride it out.
The two funds' monthly returns correlate at 0.59. They move independently enough that combining them can meaningfully diversify a portfolio.
Fees and Cost Over Time
IDNA charges 0.47% per year while VOO charges 0.03%. On a $10,000 position that is $47 vs $3 annually, a gap of $44 per year that compounds over a long holding period. On income, IDNA currently yields 0.83% against 1.09% for VOO.
Holdings Overlap
IDNA and VOO share 6 holdings out of 547 unique holdings combined, representing a 0.9% weight overlap.
Moderate overlap means holding both could provide meaningful diversification benefits.
Frequently Asked Questions
Which is cheaper, IDNA or VOO?
IDNA has an expense ratio of 0.47% while VOO charges 0.03%. VOO is the cheaper option. On a $10,000 investment, that is $44 per year of difference.
Which performed better, IDNA or VOO?
Over the past year IDNA returned +65.26% vs +21.63% for VOO, so IDNA leads on 1-year performance. Over the longest common window we track (7 years), IDNA annualized +5.75% vs +13.56% for VOO. Past performance does not guarantee future results.
Which is riskier, IDNA or VOO?
IDNA has been the more volatile fund at 25.2% annualized versus 14.1% for VOO. Worst drawdown: IDNA -68.3% vs VOO -34.3%.
Should I hold both IDNA and VOO?
IDNA and VOO have a monthly-return correlation of 0.59, so combining them can provide real diversification depending on your allocation goals.
What is the holdings overlap between IDNA and VOO?
IDNA and VOO share 6 common holdings with a 0.9% weight overlap. Combined, they hold 547 unique securities.
Which pays a higher dividend, IDNA or VOO?
IDNA yields 0.83% while VOO yields 1.09%, so VOO currently pays the higher dividend yield.
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