XBI ETF

XBI ETF
$149.29
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XBI holds 16.2% of its assets in its 10 largest positions as of Sep 11, 2026. XBI is State Street SPDR S&P Biotech ETF.

Showing the top 10 of 313 holdings · as of Sep 11, 2026
Top 10 weight
16.15%
XBI top 10 holdings, by weight
#TickerNameWeightCumulativeSharesSectorIndustry
1—Moderna therapeuticsHealth Care · Biotechnology
3.04%		3.0%2,266,461Health CareBiotechnology
2
TWST
Twist Bioscience Corp.Health Care · Biotechnology
1.82%		4.9%1,538,121Health CareBiotechnology
Share changes, sector and industry · Pro
3
NTRA
Natera Inc
1.48%		6.3%481,504
4
HALO
Halozyme Therapeutics Inc
1.48%		7.8%1,478,512
5
KYMR
Kymera Therapeutics Inc
1.43%		9.3%1,332,435
6
ORKA
Oruka Therapeutics Inc Orka
1.40%		10.7%1,627,933
7—Roivant Sciences Ltd. Common Shares
1.39%		12.0%3,668,940
8
RVMD
Revolution Medicines Inc
1.37%		13.4%722,883
9
TVTX
Travere Therapeutics Inc
1.37%		14.8%2,230,138
10
INSM
Insmed Inc
1.37%		16.2%1,134,475
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Themes in the top 10
BiotechnologyPharmaceuticalsImmunologyLife Sciences ToolsAging PopulationBiotechnology ToolsEmerging TechArtificial IntelligenceOncologyDigital Health

XBI ETF Top Holdings

XBI holdings top 10 positions. The top 10 holdings account for 16.2% of the fund, led by Moderna therapeutics at 3.0%, Twist Bioscience Corp. at 1.8%, Natera Inc at 1.5%.

XBI portfolio concentration is well-diversified, with the top 10 representing 16.2% of total assets. The largest sector exposure is Health Care at 97.7%.

XBI sectors provide a detailed breakdown. XBI overlap shows how holdings compare to other funds in your portfolio.

Compare XBI

XBI vs SPYXBI vs QQQXBI vs VOOXBI vs VTIXBI vs IVVXBI vs SCHDXBI vs VYMXBI vs VXUS
Showing 10 of 313 holdingsTop 10 Weight: 16.15%
#TickerNameIndustryWeightAllocation
1MRNAModerna therapeuticsHealth Care3.04%
2TWSTTwist Bioscience Corp.Health Care1.82%
3NTRANatera IncHealth Care1.48%
4HALOHalozyme Therapeutics IncHealth Care1.48%
5KYMRKymera Therapeutics IncHealth Care1.43%
6ORKAOruka Therapeutics Inc OrkaHealth Care1.40%
7ROIV:BMRoivant Sciences Ltd. Common SharesHealth Care1.39%
8RVMDRevolution Medicines IncHealth Care1.37%
9TVTXTravere Therapeutics IncHealth Care1.37%
10INSMInsmed IncHealth Care1.37%
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Holdings Distribution

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