CANC vs VTI
Tema Oncology ETF vs Vanguard Total Stock Market ETF
Quick Verdict
VTI has a lower expense ratio. CANC delivered stronger 1-year returns. VTI offers more diversification with 2783 holdings.
Side-by-Side Comparison
| Metric | CANC | VTI | Winner |
|---|---|---|---|
| Expense Ratio | 0.75% | 0.03% | |
| AUM | $196M | $663.5B | |
| Dividend Yield | 0.05% | 1.07% | |
| Holdings | 56 | 3,543 | |
| YTD Return | +23.01% | +14.96% | |
| 1Y Return | +61.38% | +22.39% | |
| 3Y Return (annualized) | +21.76% | +21.51% | |
| 5Y Return (annualized) | - | +12.36% | |
| Volatility (annualized) | 19.2% | 15.4% | |
| Max Drawdown | -26.1% | -56.6% | |
| Fund Family | Tema Global Limited | Vanguard (US) | |
| Category | Equity | Equity | |
| Inception | Aug 15, 2023 | May 24, 2001 |
CANC vs VTI Performance
Tema Oncology ETF (CANC) is a ETF from Tema Global Limited and Vanguard Total Stock Market ETF (VTI) is a ETF from Vanguard (US). Over the past year CANC returned +61.38% while VTI returned +22.39%. Year to date, CANC is up 23.01% versus a gain of 14.96% for VTI.
Over three years, CANC compounded at +21.76% per year against +21.51% for VTI. Across the full 3-year window we track, CANC has the edge at +21.76% annualized vs +8.16%. Past performance does not guarantee future results.
Risk: Volatility and Drawdowns
CANC has been the more volatile fund, with annualized monthly volatility of 19.2% compared with 15.4% for VTI. Lower volatility generally means a smoother ride, though it often comes with lower long-run returns.
The deepest peak-to-trough decline in our data was -26.1% for CANC and -56.6% for VTI. Drawdown depth is worth weighing if you expect to sell during market stress rather than ride it out.
The two funds' monthly returns correlate at 0.49. They move independently enough that combining them can meaningfully diversify a portfolio.
Fees and Cost Over Time
CANC charges 0.75% per year while VTI charges 0.03%. On a $10,000 position that is $75 vs $3 annually, a gap of $72 per year that compounds over a long holding period. On income, CANC currently yields 0.05% against 1.07% for VTI.
Holdings Overlap
CANC and VTI share 36 holdings out of 2804 unique holdings combined, representing a 4.2% weight overlap.
Moderate overlap means holding both could provide meaningful diversification benefits.
Frequently Asked Questions
Which is cheaper, CANC or VTI?
CANC has an expense ratio of 0.75% while VTI charges 0.03%. VTI is the cheaper option. On a $10,000 investment, that is $72 per year of difference.
Which performed better, CANC or VTI?
Over the past year CANC returned +61.38% vs +22.39% for VTI, so CANC leads on 1-year performance. Over the longest common window we track (3 years), CANC annualized +21.76% vs +8.16% for VTI. Past performance does not guarantee future results.
Which is riskier, CANC or VTI?
CANC has been the more volatile fund at 19.2% annualized versus 15.4% for VTI. Worst drawdown: CANC -26.1% vs VTI -56.6%.
Should I hold both CANC and VTI?
CANC and VTI have a monthly-return correlation of 0.49, so combining them can provide real diversification depending on your allocation goals.
What is the holdings overlap between CANC and VTI?
CANC and VTI share 36 common holdings with a 4.2% weight overlap. Combined, they hold 2804 unique securities.
Which pays a higher dividend, CANC or VTI?
CANC yields 0.05% while VTI yields 1.07%, so VTI currently pays the higher dividend yield.
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