CANC vs VTI
Tema Oncology ETF vs Vanguard Morningstar Total Stock Market ETF
Which is better, CANC or VTI?
Each has led over a different period.
VTI has a lower expense ratio. CANC led over 1Y and 3Y, VTI over the full window. VTI is less concentrated, with 33.3% of the fund in its ten largest positions against 40.2%.
MarketXLS is not an investment adviser. This comparison is generated automatically from market data and is for information only. A Best mark means the better reading on that one measure, not a recommendation to buy.
Side-by-Side Comparison
| Metric | CANC | VTI |
|---|---|---|
| Expense Ratio | 0.75% | 0.03%Best |
| AUM | $209M | $690.1B |
| Dividend Yield | 0.05% | 1.03% |
| Holdings | 118 | 3,524 |
| YTD Return | +18.51%Best | +13.35% |
| 1Y Return | +40.62%Best | +15.92% |
| 3Y Return (annualized) | +24.46%Best | +23.41% |
| 5Y Return (annualized) | - | +12.83% |
| Volatility (annualized) | 19.1% | 13.0%Best |
| Max Drawdown | -26.1% | -19.3%Best |
| $10,000 over 3.1 years | $17,277 | $17,780Best |
| Top 10 Weight | 40.2% | 33.3%Best |
| Fund Family | Tema Global Limited | Vanguard (US) |
| Category | Equity | Equity |
| Style | Large Cap Blend | Large Cap Blend |
| Inception | Aug 15, 2023 | May 24, 2001 |
Volatility and max drawdown, and the $10,000 over 3.1 years row, are measured over the window both funds cover: Aug 15, 2023 to Oct 2, 2026 (3.1 years).
CANC vs VTI growth
Month-end closes. Both lines start at 0% in the first month shown, so the gap between them is the difference in growth across that window. The full view covers the 3.1 years both funds cover.
CANC vs VTI Performance
Tema Oncology ETF (CANC) is an ETF from Tema Global Limited and Vanguard Morningstar Total Stock Market ETF (VTI) is an ETF from Vanguard (US). Over the past year CANC returned +40.62% while VTI returned +15.92%. Year to date, CANC is up 18.51% versus a gain of 13.35% for VTI.
Over three years, CANC compounded at +24.46% per year against +23.41% for VTI.
Past performance does not guarantee future results.
Risk: Volatility and Drawdowns
CANC has been the more volatile fund, with annualized monthly volatility of 19.1% compared with 13.0% for VTI. Lower volatility generally means a smoother ride, though it often comes with lower long-run returns.
The deepest peak-to-trough decline in our data was -26.1% for CANC and -19.3% for VTI. Drawdown depth is what each fund did in the worst stretch of the window measured above.
The two funds' monthly returns correlate at 0.49. They move together some of the time, and apart the rest.
Fees and Cost Over Time
CANC charges 0.75% per year while VTI charges 0.03%. On a $10,000 position that is $75 vs $3 annually, a gap of $72 per year that compounds over a long holding period. On income, CANC currently yields 0.05% against 1.03% for VTI.
Holdings Overlap
77.7% of CANC's money is in holdings VTI also owns. 4.2% of VTI's money is in holdings CANC also owns.
Most of CANC is already inside VTI. Owning both mostly buys the same companies twice.
46 positions in common, counted across the 59 positions we hold weights for in CANC and 3,463 in VTI, against full books of 118 and 3,524.
What only one of them owns
Our book lists 1,130 positions for VTI that do not appear in our book for CANC (93.2% of the fund), and 4 for CANC that do not appear in VTI (6.3%).
Some of those will be the same company recorded under a different code in one of the two books, so the real difference in what you would own is no larger than this and may be smaller. We do not name the individual positions here for that reason.
Top Shared Holdings
| Stock | Weight in CANC | Weight in VTI | Difference |
|---|---|---|---|
| LLYEli Lilly & Co. | 4.54% | 1.35% | 3.19% |
| RVMDRevolution Medicines Inc | 5.55% | 0.05% | 5.50% |
| MRKMerck & Company Inc | 4.68% | 0.45% | 4.23% |
| COGTCogent Biosciences Inc | 4.99% | 0.01% | 4.98% |
| ABBVAbbvie Inc. | 3.55% | 0.61% | 2.94% |
| JNJJohnson & Johnson - Common | 3.24% | 0.86% | 2.38% |
| BMYBristol-Myers Squibb Co. | 3.59% | 0.18% | 3.41% |
| HALOHalozyme Therapeutics Inc | 3.07% | 0.01% | 3.06% |
| EXELExelixis Inc | 2.83% | 0.02% | 2.81% |
| CGONCg Oncology Inc | 2.84% | 0.01% | 2.83% |
77.7% of CANC is already inside VTI.
You probably hold more than these two. Add the rest and see how much of the whole book is the same companies twice.
Free for up to 10 holdings. No account needed.
Frequently Asked Questions
Which is cheaper, CANC or VTI?
CANC has an expense ratio of 0.75% while VTI charges 0.03%. VTI is the cheaper option, by $72 a year on a $10,000 investment.
Which performed better, CANC or VTI?
Over the past year CANC returned +40.62% vs +15.92% for VTI, so CANC leads on 1-year performance. Past performance does not guarantee future results. This is information, not a recommendation.
Which is riskier, CANC or VTI?
CANC has been the more volatile fund at 19.1% annualized versus 13.0% for VTI. Worst drawdown: CANC -26.1% vs VTI -19.3%.
Should I hold both CANC and VTI?
CANC and VTI have a monthly-return correlation of 0.49, so their returns are far enough apart for the mix to behave differently from either one alone. This is information, not a recommendation.
What is the holdings overlap between CANC and VTI?
77.7% of CANC's money is in holdings VTI also owns. 4.2% of VTI's is in holdings CANC also owns. They hold 46 positions in common, counted across the 59 positions we hold weights for in CANC and 3,463 in VTI.
Which pays a higher dividend, CANC or VTI?
CANC yields 0.05% while VTI yields 1.03%, so VTI currently pays the higher dividend yield.
Is VTI better than CANC?
VTI has a lower expense ratio. CANC led over 1Y and 3Y, VTI over the full window. VTI is less concentrated, with 33.3% of the fund in its ten largest positions against 40.2%. Which one suits a particular account depends on what it is for. This is information, not a recommendation.