XPH ETF largest holding is DFTX:CA at 2.88% as of Jun 30, 2026

XPH ETF largest holding is DFTX:CA at 2.88% as of Jun 30, 2026
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DFTX:CA is XPH's largest holding at 2.88% of the fund as of Jun 30, 2026. XPH is State Street SPDR S&P Pharmaceuticals ETF.

Showing top 50 of 67 holdings · as of Jun 30, 2026
XPH holdings, by weight
#TickerNameWeightCumulativeSharesSectorIndustry
1—Definium Therapeutics, Inc. Common Shares
2.88%		2.9%290,045--
2
MBX
Mbx Biosciences IncHealth Care · Biotechnology
2.81%		5.7%217,506Health CareBiotechnology
Share changes, sector and industry · Pro
3
ALMS
Alumis Inc
2.05%		7.7%336,026
4
ELVN
Enliven Therapeutics Inc
2.04%		9.8%182,178
5
TRVI
Trevi Therapeutics Inc.
2.02%		11.8%503,029
6
AMLX
Amylyx Pharmaceuticals Inc
2.01%		13.8%500,791
7
MAZE
Maze Therapeutics Inc
1.98%		15.8%274,078
8
MANE
Veradermics Inc
1.98%		17.8%72,490
9—Ataibeckley Inc.
1.98%		19.8%1,783,234
10
LGND
Ligand Pharmaceuticals, Inc.
1.95%		21.7%27,150
11
NKTR
Nektar Therapeutics Class A
1.94%		23.6%118,714
12—Harrow Health Inc
1.89%		25.5%187,760
13
CRNX
Crinetics Pharmaceuticals Inc
1.85%		27.4%196,404
14
EWTX
Edgewise Therapeutics Inc.
1.84%		29.2%204,753
15
NUVB
Nuvation Bio Inc
1.84%		31.1%1,471,749
16—Liquidia Technologies Inc
1.83%		32.9%103,303
17
CORT
Corcept Therapeutics Inc
1.77%		34.7%86,284
18
EYPT
Eyepoint Pharmaceuticals Inc.(eypt)
1.77%		36.4%546,682
19
WVE
Wave Life Sciences Ltd
1.68%		38.1%1,190,929
20
AMRX
Amneal Pharmaceuticals Inc.
1.67%		39.8%439,990
21
OCUL
Ocular Therapeutix Inc
1.67%		41.5%771,241
22
ELAN
Elanco Animal Health, Inc Cvr
1.66%		43.1%294,733
23—Pacira Pharm Inc
1.65%		44.8%287,812
24
TARS
Tarsus Pharmaceuticals Inc
1.65%		46.4%110,021
25
JNJ
Johnson & Johnson -
1.64%		48.1%28,269
26
COLL
Collegium Pharmaceutical Inc
1.62%		49.7%193,694
27
VTRS
Viatris Inc.
1.61%		51.3%427,432
28
MRK
Merck & Company Inc
1.60%		52.9%56,604
29
JAZZ
Jazz Pharmaceuticals Plc.
1.60%		54.5%29,357
30
LLY
Eli Lilly & Co.
1.59%		56.1%5,937
31—Indivior Pharmaceuticals, Inc. Ordinary Shares
1.58%		57.7%176,962
32
SUPN
Supernus Pharmaceuticals Inc
1.58%		59.2%149,499
33
ANIP
Ani Pharmaceuticals Inc
1.57%		60.8%82,359
34
HRMY
Harmony Biosciences, Llc
1.57%		62.4%189,981
35
RPRX
Royalty Pharma Plc Class A Ordinary Share
1.57%		63.9%123,635
36
BMY
Bristol-Myers Squibb Co.
1.54%		65.5%121,234
37
OMER
Omeros Corp
1.53%		67.0%660,846
38
OGN
Organon & Co
1.53%		68.5%503,786
39
ESPR
Esperion Therapeutics Inc
1.51%		70.1%2,146,699
40
BIOA
Bioage Labs Inc
1.50%		71.6%270,285
41
PBH
Prestige Consumer Healthcare Inc
1.50%		73.1%137,198
42
PRGO
Perrigo Company Plc Ordinary Shares
1.50%		74.6%603,461
43
AXSM
Axsome Therapeutics, Inc.
1.48%		76.0%27,365
44—Xeris Pharmaceuticals Inc
1.45%		77.5%776,677
45
INVA
Innoviva Inc
1.43%		78.9%293,075
46
PFE
Pfizer Inc
1.40%		80.3%263,309
47
ZTS
Zoetis Inc, Class A
1.40%		81.7%82,924
48
PAHC
Phibro Animal Health Corp
1.38%		83.1%180,645
49
ETON
Eton Pharmaceuticals Inc.
1.35%		84.4%159,226
50
RAPP
Rapport Therapeutics, Inc.
1.32%		85.8%152,442
More holdings · Pro
Not reported for this fund: market value.
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XPH ETF All Holdings

XPH holdings total 67 positions. The top 10 holdings account for 21.7% of the fund, led by Definium Therapeutics, Inc. Common Shares at 2.9%, Mbx Biosciences Inc at 2.8%, Alumis Inc Common Stock USD 0.0001 at 2.0%.

XPH portfolio concentration is well-diversified, with the top 10 representing 21.7% of total assets. The largest sector exposure is Health Care at 84.1%.

XPH sectors provide a detailed breakdown. XPH overlap shows how holdings compare to other funds in your portfolio.

Compare XPH

XPH vs SPYXPH vs QQQXPH vs VOOXPH vs VTIXPH vs IVVXPH vs SCHDXPH vs VYMXPH vs VXUS

XPH ETF Holdings

67 of 67 holdings

  • 1

    Definium Therapeutics, Inc. Common Shares

    DFTX:CAUnknown
    2.88%
  • 2

    Mbx Biosciences Inc

    MBXHealth Care
    2.81%
  • 3

    Alumis Inc Common Stock USD 0.0001

    ALMSIndustrials
    2.05%
  • 4

    Enliven Therapeutics Inc

    ELVNHealth Care
    2.04%
  • 5

    Trevi Therapeutics Inc.

    TRVIHealth Care
    2.02%
  • 6

    Amylyx Pharmaceuticals Inc

    AMLXHealth Care
    2.01%
  • 7

    Maze Therapeutics Inc

    MAZEHealth Care
    1.98%
  • 8

    Veradermics Inc

    MANEUnknown
    1.98%
  • 9

    Ataibeckley Inc.

    ATAIHealth Care
    1.98%
  • 10

    Ligand Pharmaceuticals, Inc.

    LGNDHealth Care
    1.95%
  • 11

    Nektar Therapeutics Class A

    NKTRUnknown
    1.94%
  • 12

    Harrow Health Inc Com

    HROWHealth Care
    1.89%
  • 13

    Crinetics Pharmaceuticals Inc Com

    CRNXHealth Care
    1.85%
  • 14

    Edgewise Therapeutics Inc.

    EWTXHealth Care
    1.84%
  • 15

    Nuvation Bio Inc

    NUVBHealth Care
    1.84%
  • 16

    Liquidia Technologies Inc

    LQDAHealth Care
    1.83%
  • 17

    Corcept Therapeutics Incorporated

    CORTHealth Care
    1.77%
  • 18

    Eyepoint Pharmaceuticals Inc.(eypt)

    EYPTHealth Care
    1.77%
  • 19

    Wave Life Sciences Ltd

    WVEHealth Care
    1.68%
  • 20

    Amneal Pharmaceuticals Inc.

    AMRXHealth Care
    1.67%
  • 21

    Ocular Therapeutix Inc

    OCULHealth Care
    1.67%
  • 22

    Elanco Animal Health, Inc Cvr

    ELANHealth Care
    1.66%
  • 23

    Pacira Pharm Inc

    PCRXHealth Care
    1.65%
  • 24

    Tarsus Pharmaceuticals Inc

    TARSHealth Care
    1.65%
  • 25

    Johnson & Johnson - Common

    JNJHealth Care
    1.64%
  • 26

    Collegium Pharmaceutical Inc

    COLLHealth Care
    1.62%
  • 27

    Viatris Inc.

    VTRSHealth Care
    1.61%
  • 28

    Merck & Company Inc

    MRKHealth Care
    1.60%
  • 29

    Jazz Pharmaceuticals Plc.

    JAZZHealth Care
    1.60%
  • 30

    Eli Lilly & Co.

    LLYHealth Care
    1.59%
  • 31

    Indivior Pharmaceuticals, Inc. Ordinary Shares

    INDV:MBUnknown
    1.58%
  • 32

    Supernus Pharmaceuticals Inc

    SUPNHealth Care
    1.58%
  • 33

    Ani Pharmaceuticals Inc

    ANIPHealth Care
    1.57%
  • 34

    Harmony Biosciences, Llc

    HRMYHealth Care
    1.57%
  • 35

    Royalty Pharma Plc Class A Ordinary Share

    RPD:DUFinancials
    1.57%
  • 36

    Bristol-Myers Squibb Co.

    BMYHealth Care
    1.54%
  • 37

    Omeros Corp Com

    OMERHealth Care
    1.53%
  • 38

    Organon & Co

    OGNHealth Care
    1.53%
  • 39

    Esperion Therapeutics Inc

    ESPRHealth Care
    1.51%
  • 40

    Bioage Labs Inc Common Stock Usd.00001

    BIOAHealth Care
    1.50%
  • 41

    Prestige Consumer Healthcare Inc

    PBHConsumer Staples
    1.50%
  • 42

    Perrigo Company Plc Ordinary Shares

    PRGOConsumer Staples
    1.50%
  • 43

    Axsome Therapeutics, Inc.

    AXSMHealth Care
    1.48%
  • 44

    Xeris Pharmaceuticals Inc Com

    XERSHealth Care
    1.45%
  • 45

    Innoviva Inc

    INVAHealth Care
    1.43%
  • 46

    Pfizer Inc

    PFEHealth Care
    1.40%
  • 47

    Zoetis Inc, Class A

    ZTSHealth Care
    1.40%
  • 48

    Phibro Animal Health Corp

    PAHCHealth Care
    1.38%
  • 49

    Eton Pharmaceuticals Inc.

    ETONHealth Care
    1.35%
  • 50

    Rapport Therapeutics, Inc.

    RAPPHealth Care
    1.32%
  • 51

    Arvinas Inc

    ARVNHealth Care
    1.25%
  • 52

    Amphastar Pharmaceuticals Inc

    AMPHHealth Care
    1.20%
  • 53

    Zevra Therapeutics Inc

    ZVRAHealth Care
    1.19%
  • 54

    Alto Neuroscience, Inc., Series C

    ANROHealth Care
    1.15%
  • 55

    Cormedix Inc Com

    CRMDHealth Care
    1.11%
  • 56

    Phathom Pharmaceuticals Inc Phat

    PHATHealth Care
    1.10%
  • 57

    Septerna Inc

    SEPNHealth Care
    0.98%
  • 58

    Relmada Therapeutics Inc Common Stock

    RLMDHealth Care
    0.96%
  • 59

    Theravance Biopharma Inc

    TBPHHealth Care
    0.95%
  • 60

    Aclaris Therapeutics Inc

    ACRSHealth Care
    0.92%
  • 61

    Lb Pharmaceuticals Inc.

    LBRXUnknown
    0.81%
  • 62

    Ara Us Hospitality Trust

    AQSTHealth Care
    0.77%
  • 63

    Fulcrum Therapeutics Inc Com

    FULCHealth Care
    0.69%
  • 64

    Lexicon Pharmaceut Com New

    LXRXHealth Care
    0.60%
  • 65

    Evolus Inc

    EOLSHealth Care
    0.52%
  • 66

    Ssi Us Gov Money Market Class

    NMFUnknown
    0.06%
  • 67

    US Dollar

    Other
    0.00%