SBIO ETF
ALPS Medical Breakthroughs ETF
CRNX is SBIO's largest holding at 4.60% of the fund as of Aug 31, 2026. SBIO is ALPS Medical Breakthroughs ETF.
| # | Ticker | Name | Weight | Cumulative | Shares | Mkt value | Sector | Industry |
|---|---|---|---|---|---|---|---|---|
| 1 |  C | Crinetics Pharmaceuticals IncHealth Care · Pharmaceuticals | 4.60% | 4.6% | 129,887 | $11.03M | Health Care | Pharmaceuticals |
| 2 | — | Allogene Therapeutics IncHealth Care · Biotechnology | 4.29% | 8.9% | 76,303 | $10.31M | Health Care | Biotechnology |
| Sector and industry · Pro | ||||||||
| 3 |  C | Cg Oncology Inc | 3.41% | 12.3% | 108,748 | $8.17M | ||
| 4 |  T | Travere Therapeutics Inc | 3.16% | 15.5% | 114,580 | $7.59M | ||
| 5 | — | Xenon Pharmaceuticals Inc. Common Shares | 2.99% | 18.5% | 119,032 | $7.17M | ||
| 6 |  D | Dianthus Therapeutics Inc | 2.96% | 21.4% | 67,349 | $7.11M | ||
| 7 |  O | Oruka Therapeutics Inc Orka | 2.87% | 24.3% | 74,239 | $6.88M | ||
| 8 |  A | Acadia Pharmaceuticals Inc | 2.54% | 26.8% | 210,911 | $6.10M | ||
| 9 |  E | Edgewise Therapeutics Inc. | 2.31% | 29.1% | 132,744 | $5.54M | ||
| 10 | — | Definium Therapeutics, Inc. Common Shares | 2.23% | 31.4% | 134,472 | $5.34M | ||
| 11 |  D | Dyne Therapeutics Inc | 2.16% | 33.5% | 203,881 | $5.18M | ||
| 12 |  M | Veradermics Inc | 2.11% | 35.6% | 51,414 | $5.06M | ||
| 13 |  R | Relay Therapeutics Inc | 2.05% | 37.7% | 268,305 | $4.93M | ||
| 14 |  D | Denali Therapeutics Inc | 1.94% | 39.6% | 195,712 | $4.65M | ||
| 15 |  A | Amylyx Pharmaceuticals Inc | 1.93% | 41.5% | 137,199 | $4.63M | ||
| 16 |  I | Ideaya Biosciences Inc | 1.81% | 43.4% | 108,324 | $4.34M | ||
| 17 | — | Structure Therapeutics Inc Adr | 1.68% | 45.0% | 87,652 | $4.02M | ||
| 18 |  T | Tarsus Pharmaceuticals Inc | 1.64% | 46.7% | 52,936 | $3.93M | ||
| 19 |  C | Celldex Therapeutics Inc | 1.60% | 48.3% | 96,637 | $3.83M | ||
| 20 |  I | Immunome Inc | 1.60% | 49.9% | 139,649 | $3.83M | ||
| 21 |  I | Disc Medicine Inc | 1.54% | 51.4% | 47,067 | $3.70M | ||
| 22 |  N | Newamsterdam Pharma Company Nv | 1.52% | 52.9% | 144,171 | $3.65M | ||
| 23 |  M | Mbx Biosciences Inc | 1.50% | 54.4% | 58,603 | $3.61M | ||
| 24 |  Z | Zai Lab Ltd | 1.42% | 55.9% | 134,267 | $3.42M | ||
| 25 |  V | Viridian Therapeutics Inc | 1.31% | 57.2% | 136,151 | $3.15M | ||
| 26 |  S | Sellas Life Sciences Group Inc. | 1.28% | 58.5% | 229,519 | $3.06M | ||
| 27 |  B | BioCryst Pharmaceuticals Inc. | 1.27% | 59.7% | 313,539 | $3.04M | ||
| 28 |  V | Vera Therapeutics Inc Ser C Pc Pp | 1.26% | 61.0% | 88,541 | $3.02M | ||
| 29 |  N | Nektar Therapeutics | 1.24% | 62.2% | 41,702 | $2.98M | ||
| 30 |  N | Nuvation Bio Inc | 1.19% | 63.4% | 429,510 | $2.86M | ||
| 31 |  R | Rapport Therapeutics, Inc. | 1.19% | 64.6% | 58,886 | $2.87M | ||
| 32 |  M | Mineralys Therapeutics Inc | 1.16% | 65.8% | 108,606 | $2.79M | ||
| 33 |  S | Sarepta Therapeutics Inc | 1.14% | 66.9% | 130,053 | $2.74M | ||
| 34 |  P | Palvella Therapeutics Inc | 1.12% | 68.0% | 17,554 | $2.68M | ||
| 35 |  V | Vericel Corp | 1.05% | 69.1% | 62,891 | $2.51M | ||
| 36 |  Z | Zenas Biopharma Inc | 1.05% | 70.1% | 77,726 | $2.51M | ||
| 37 |  X | Xencor Inc | 1.04% | 71.2% | 91,156 | $2.49M | ||
| 38 |  A | Agios Pharmaceuticals Inc | 1.03% | 72.2% | 73,293 | $2.47M | ||
| 39 |  K | Kailera Therapeutics Inc | 1.03% | 73.2% | 159,843 | $2.46M | ||
| 40 |  G | Generate Biomedicines Inc | 1.00% | 74.2% | 157,939 | $2.41M | ||
| 41 |  S | Stoke Therapeuti | 1.00% | 75.2% | 76,868 | $2.40M | ||
| 42 |  L | Lakefront Biotherapeutics Sponsored Adr (1 Ads : 1 Ordinary) | 0.95% | 76.2% | 80,031 | $2.28M | ||
| 43 | — | Immunocore Holdings Ltd Adr | 0.95% | 77.1% | 62,739 | $2.28M | ||
| 44 |  C | Compass Pathways Plc Adr | 0.94% | 78.1% | 166,501 | $2.25M | ||
| 45 |  T | Taysha Gene Therapies Inc | 0.84% | 78.9% | 354,512 | $2.02M | ||
| 46 |  B | Bicara Therapeutics, Inc. | 0.78% | 79.7% | 80,805 | $1.87M | ||
| 47 |  T | Tyra Biosciences Inc | 0.77% | 80.5% | 73,393 | $1.84M | ||
| 48 |  M | Maze Therapeutics Inc | 0.76% | 81.2% | 68,294 | $1.81M | ||
| 49 |  A | Arrivent Biopharma Inc | 0.72% | 81.9% | 57,448 | $1.73M | ||
| 50 |  L | Lb Pharmaceuticals Inc. | 0.70% | 82.6% | 35,483 | $1.68M | ||
| More holdings · Pro | ||||||||
SBIO ETF All Holdings
SBIO holdings total 107 positions. The top 10 holdings account for 31.4% of the fund, led by Crinetics Pharmaceuticals Inc Com at 4.6%, Allogene Therapeutics Inc at 4.3%, Cg Oncology Inc at 3.4%.
SBIO portfolio concentration is moderate, with the top 10 representing 31.4% of total assets. The largest sector exposure is Health Care at 88.7%.
SBIO sectors provide a detailed breakdown. SBIO overlap shows how holdings compare to other funds in your portfolio.
SBIO ETF Holdings
107 of 107 holdings
- 1
Crinetics Pharmaceuticals Inc Com
CRNXHealth Care4.60% - 2
Allogene Therapeutics Inc
APGEHealth Care4.29% - 3
Cg Oncology Inc
CGONHealth Care3.41% - 4
Travere Therapeutics Inc
TVTXHealth Care3.16% - 5
Xenon Pharmaceuticals Inc. Common Shares
XENE:CAHealth Care2.99% - 6
Dianthus Therapeutics Inc
DNTHHealth Care2.96% - 7
Oruka Therapeutics Inc Orka
ORKAHealth Care2.87% - 8
Acadia Pharmaceuticals Inc Common Stock Usd 0.0001
ACADHealth Care2.54% - 9
Edgewise Therapeutics Inc.
EWTXHealth Care2.31% - 10
Definium Therapeutics, Inc. Common Shares
DFTX:CAUnknown2.23% - 11
Dyne Therapeutics Inc
DYNHealth Care2.16% - 12
Veradermics Inc
MANEUnknown2.11% - 13
Relay Therapeutics Inc
RLAYHealth Care2.05% - 14
Denali Therapeutics Inc
DNLIHealth Care1.94% - 15
Amylyx Pharmaceuticals Inc
AMLXHealth Care1.93% - 16
Ideaya Biosciences Inc
IDYAHealth Care1.81% - 17
Structure Therapeutics Inc Adr
GPCR:SHHealth Care1.68% - 18
Tarsus Pharmaceuticals Inc
TARSHealth Care1.64% - 19
Celldex Therapeutics Inc
CLDXHealth Care1.60% - 20
Immunome Inc
IMNMHealth Care1.60% - 21
Disc Medicine Inc
IRONHealth Care1.54% - 22
Newamsterdam Pharma Company Nv
NAMSHealth Care1.52% - 23
Mbx Biosciences Inc
MBXHealth Care1.50% - 24
Zai Lab Ltd
ZLABHealth Care1.42% - 25
Viridian Therapeutics Inc
VRDNHealth Care1.31% - 26
Sellas Life Sciences Group Inc.
SLSHealth Care1.28% - 27
BioCryst Pharmaceuticals Inc.
BCRXHealth Care1.27% - 28
Vera Therapeutics Inc Ser C Pc Pp
VERAHealth Care1.26% - 29
Nektar Therapeutics Common Stock Usd.0001
NKTRHealth Care1.24% - 30
Nuvation Bio Inc
NUVBHealth Care1.19% - 31
Rapport Therapeutics, Inc.
RAPPHealth Care1.19% - 32
Mineralys Therapeutics Inc
MLYSHealth Care1.16% - 33
Sarepta Therapeutics Inc
SRPTHealth Care1.14% - 34
Palvella Therapeutics Inc
PVLAHealth Care1.12% - 35
Vericel Corp
VCELHealth Care1.05% - 36
Zenas Biopharma Inc
ZBIOHealth Care1.05% - 37
Xencor Inc
XNCRHealth Care1.04% - 38
Agios Pharmaceuticals Inc
AGIOHealth Care1.03% - 39
Kailera Therapeutics Inc
KLRAUnknown1.03% - 40
Generate Biomedicines Inc
GENBUnknown1.00% - 41
Stoke Therapeuti
STOKHealth Care1.00% - 42
Lakefront Biotherapeutics Sponsored Adr (1 Ads : 1 Ordinary)
GLPG:BRHealth Care0.95% - 43
Immunocore Holdings Ltd Adr
IMCR:LNHealth Care0.95% - 44
Compass Pathways Plc Adr
CMPSHealth Care0.94% - 45
Taysha Gene Therapies Inc
TSHAHealth Care0.84% - 46
Bicara Therapeutics, Inc.
BCAXHealth Care0.78% - 47
Tyra Biosciences Inc
TYRAHealth Care0.77% - 48
Maze Therapeutics Inc
MAZEHealth Care0.76% - 49
ARRIVENT BIOPHARMA INC
AVBPHealth Care0.72% - 50
Lb Pharmaceuticals Inc.
LBRXUnknown0.70% - 51
Immatics Nv
4A3:BEHealth Care0.66% - 52
Seaport Therapeutics Inc
SPTXUnknown0.65% - 53
Meiragtx Holdings Plc Com Usd0.00003881
MGTXHealth Care0.65% - 54
Alto Neuroscience, Inc., Series C
ANROHealth Care0.64% - 55
Mannkind Corp.
MNKDHealth Care0.64% - 56
Vor Biopharma, Inc.
VORUnknown0.62% - 57
Corvus Pharmaceuticals Inc
CRVSHealth Care0.61% - 58
Kura Oncology Inc
KURAHealth Care0.58% - 59
Candel Therapeutics Inc.
CADLHealth Care0.49% - 60
Design Therapeutics Inc.
DSGNHealth Care0.49% - 61
Geron Corp
GERNHealth Care0.49% - 62
Solid Biosciences Inc
SLDBHealth Care0.49% - 63
Wave Life Sciences Ltd
WVEHealth Care0.48% - 64
Olema Pharmaceuticals Inc
OLMAHealth Care0.47% - 65
Theravance Biopharma Inc
TBPHHealth Care0.45% - 66
Aclaris Therapeutics Inc
ACRSHealth Care0.44% - 67
Rigel Pharmaceuticals Inc Common Stock USD.001
RIGLHealth Care0.44% - 68
Spyglass Pharma Inc
SGPUnknown0.43% - 69
Climb Bio Inc
CLYMHealth Care0.41% - 70
4d Molecular Therapeutics Inc.
FDMTHealth Care0.38% - 71
Oculis Holding Ag
OCS:SMUnknown0.36% - 72
Allogene Therapeutics
NPCUFUnknown0.36% - 73
AgomAb Therapeutics NV Each ADS represents one common share
AGMB:BRUnknown0.33% - 74
Altimmune Inc
ALTHealth Care0.31% - 75
NEURogene
NGNEUnknown0.30% - 76
Delcath Sys Inc
DCTHHealth Care0.29% - 77
Eikon Therapeutics Inc
EIKNUnknown0.29% - 78
Tectonic Therapeutic Inc Pipe
TECXHealth Care0.29% - 79
Fulgent Genetics Inc
FLGTHealth Care0.28% - 80
Contineum Therapeutics, Inc.
CTNMHealth Care0.27% - 81
ZURA BIO LTD COMMON STOCK
ZURA:KYUnknown0.27% - 82
Evommune Inc
EVMNUnknown0.24% - 83
Relmada Therapeutics Inc Common Stock
RLMDHealth Care0.24% - 84
Rezolute Inc Pipe Deal Rzlt
RZLTHealth Care0.23% - 85
COMPASS THERAPEUTICS INC
CMPXHealth Care0.22% - 86
Arcturus Therapeutics Holdings Inc.
ARCTUnknown0.22% - 87
C4 Therapeutics Inc
CCCCHealth Care0.21% - 88
Enanta Pharmaceuticals Inc
ENTAHealth Care0.20% - 89
X4 Pharmaceuticals Inc
XFORHealth Care0.20% - 90
Upstream Bio Inc
UPBHealth Care0.19% - 91
Immuneering Corp.
IMRXHealth Care0.17% - 92
Inhibikase Thera
IKTHealth Care0.16% - 93
Sab Biotherapeutics, Inc.
SABSHealth Care0.15% - 94
Sionna Therapeutics Inc
SIONHealth Care0.14% - 95
Akebia Therapeutics Inc
AKBAHealth Care0.13% - 96
Anavex Life Scienc Com New
AVXLHealth Care0.13% - 97
Fulcrum Therapeutics Inc Com
FULCHealth Care0.13% - 98
Macrogenics Inc
MGNXHealth Care0.13% - 99
Bicycle Therapeutics Plc-Adr
BCYC:LNHealth Care0.11% - 100
I Mab
IMABUnknown0.11% - 101
Immunic Inc.
IMUXUnknown0.11% - 102
Protara Therapeutics Inc
TARAHealth Care0.11% - 103
Tenax Therapeutics Inc
TENXUnknown0.03% - 104
Contra Chinook Therape
KDNYUnknown0.00% - 105
AstraZeneca PLC
AZN:LNUnknown0.00% - 106
Novo Nordisk A/S
Other0.00% - 107
Cash Equivalent
Other-0.05%
| # | Company | Ticker | Sector | Industry | Weight |
|---|---|---|---|---|---|
| 1 | Crinetics Pharmaceuticals Inc Com | CRNX | 4.600% | ||
| 2 | Allogene Therapeutics Inc | APGE | 4.290% | ||
| 3 | Cg Oncology Inc | CGON | 3.410% | ||
| 4 | Travere Therapeutics Inc | TVTX | 3.160% | ||
| 5 | Xenon Pharmaceuticals Inc. Common Shares | XENE:CA | 2.990% | ||
| 6 | Dianthus Therapeutics Inc | DNTH | 2.960% | ||
| 7 | Oruka Therapeutics Inc Orka | ORKA | 2.870% | ||
| 8 | Acadia Pharmaceuticals Inc Common Stock Usd 0.0001 | ACAD | 2.540% | ||
| 9 | Edgewise Therapeutics Inc. | EWTX | 2.310% | ||
| 10 | Definium Therapeutics, Inc. Common Shares | DFTX:CA | 2.230% | ||
| 11 | Dyne Therapeutics Inc | DYN | 2.160% | ||
| 12 | Veradermics Inc | MANE | 2.110% | ||
| 13 | Relay Therapeutics Inc | RLAY | 2.050% | ||
| 14 | Denali Therapeutics Inc | DNLI | 1.940% | ||
| 15 | Amylyx Pharmaceuticals Inc | AMLX | 1.930% | ||
| 16 | Ideaya Biosciences Inc | IDYA | 1.810% | ||
| 17 | Structure Therapeutics Inc Adr | GPCR:SH | 1.680% | ||
| 18 | Tarsus Pharmaceuticals Inc | TARS | 1.640% | ||
| 19 | Celldex Therapeutics Inc | CLDX | 1.600% | ||
| 20 | Immunome Inc | IMNM | 1.600% | ||
| 21 | Disc Medicine Inc | IRON | 1.540% | ||
| 22 | Newamsterdam Pharma Company Nv | NAMS | 1.520% | ||
| 23 | Mbx Biosciences Inc | MBX | 1.500% | ||
| 24 | Zai Lab Ltd | ZLAB | 1.420% | ||
| 25 | Viridian Therapeutics Inc | VRDN | 1.310% | ||
| 26 | Sellas Life Sciences Group Inc. | SLS | 1.280% | ||
| 27 | BioCryst Pharmaceuticals Inc. | BCRX | 1.270% | ||
| 28 | Vera Therapeutics Inc Ser C Pc Pp | VERA | 1.260% | ||
| 29 | Nektar Therapeutics Common Stock Usd.0001 | NKTR | 1.240% | ||
| 30 | Nuvation Bio Inc | NUVB | 1.190% | ||
| 31 | Rapport Therapeutics, Inc. | RAPP | 1.190% | ||
| 32 | Mineralys Therapeutics Inc | MLYS | 1.160% | ||
| 33 | Sarepta Therapeutics Inc | SRPT | 1.140% | ||
| 34 | Palvella Therapeutics Inc | PVLA | 1.120% | ||
| 35 | Vericel Corp | VCEL | 1.050% | ||
| 36 | Zenas Biopharma Inc | ZBIO | 1.050% | ||
| 37 | Xencor Inc | XNCR | 1.040% | ||
| 38 | Agios Pharmaceuticals Inc | AGIO | 1.030% | ||
| 39 | Kailera Therapeutics Inc | KLRA | 1.030% | ||
| 40 | Generate Biomedicines Inc | GENB | 1.000% | ||
| 41 | Stoke Therapeuti | STOK | 1.000% | ||
| 42 | Lakefront Biotherapeutics Sponsored Adr (1 Ads : 1 Ordinary) | GLPG:BR | 0.950% | ||
| 43 | Immunocore Holdings Ltd Adr | IMCR:LN | 0.950% | ||
| 44 | Compass Pathways Plc Adr | CMPS | 0.940% | ||
| 45 | Taysha Gene Therapies Inc | TSHA | 0.840% | ||
| 46 | Bicara Therapeutics, Inc. | BCAX | 0.780% | ||
| 47 | Tyra Biosciences Inc | TYRA | 0.770% | ||
| 48 | Maze Therapeutics Inc | MAZE | 0.760% | ||
| 49 | ARRIVENT BIOPHARMA INC | AVBP | 0.720% | ||
| 50 | Lb Pharmaceuticals Inc. | LBRX | 0.700% | ||
| 51 | Immatics Nv | 4A3:BE | 0.660% | ||
| 52 | Seaport Therapeutics Inc | SPTX | 0.650% | ||
| 53 | Meiragtx Holdings Plc Com Usd0.00003881 | MGTX | 0.650% | ||
| 54 | Alto Neuroscience, Inc., Series C | ANRO | 0.640% | ||
| 55 | Mannkind Corp. | MNKD | 0.640% | ||
| 56 | Vor Biopharma, Inc. | VOR | 0.620% | ||
| 57 | Corvus Pharmaceuticals Inc | CRVS | 0.610% | ||
| 58 | Kura Oncology Inc | KURA | 0.580% | ||
| 59 | Candel Therapeutics Inc. | CADL | 0.490% | ||
| 60 | Design Therapeutics Inc. | DSGN | 0.490% | ||
| 61 | Geron Corp | GERN | 0.490% | ||
| 62 | Solid Biosciences Inc | SLDB | 0.490% | ||
| 63 | Wave Life Sciences Ltd | WVE | 0.480% | ||
| 64 | Olema Pharmaceuticals Inc | OLMA | 0.470% | ||
| 65 | Theravance Biopharma Inc | TBPH | 0.450% | ||
| 66 | Aclaris Therapeutics Inc | ACRS | 0.440% | ||
| 67 | Rigel Pharmaceuticals Inc Common Stock USD.001 | RIGL | 0.440% | ||
| 68 | Spyglass Pharma Inc | SGP | 0.430% | ||
| 69 | Climb Bio Inc | CLYM | 0.410% | ||
| 70 | 4d Molecular Therapeutics Inc. | FDMT | 0.380% | ||
| 71 | Oculis Holding Ag | OCS:SM | 0.360% | ||
| 72 | Allogene Therapeutics | NPCUF | 0.360% | ||
| 73 | AgomAb Therapeutics NV Each ADS represents one common share | AGMB:BR | 0.330% | ||
| 74 | Altimmune Inc | ALT | 0.310% | ||
| 75 | NEURogene | NGNE | 0.300% | ||
| 76 | Delcath Sys Inc | DCTH | 0.290% | ||
| 77 | Eikon Therapeutics Inc | EIKN | 0.290% | ||
| 78 | Tectonic Therapeutic Inc Pipe | TECX | 0.290% | ||
| 79 | Fulgent Genetics Inc | FLGT | 0.280% | ||
| 80 | Contineum Therapeutics, Inc. | CTNM | 0.270% | ||
| 81 | ZURA BIO LTD COMMON STOCK | ZURA:KY | 0.270% | ||
| 82 | Evommune Inc | EVMN | 0.240% | ||
| 83 | Relmada Therapeutics Inc Common Stock | RLMD | 0.240% | ||
| 84 | Rezolute Inc Pipe Deal Rzlt | RZLT | 0.230% | ||
| 85 | COMPASS THERAPEUTICS INC | CMPX | 0.220% | ||
| 86 | Arcturus Therapeutics Holdings Inc. | ARCT | 0.220% | ||
| 87 | C4 Therapeutics Inc | CCCC | 0.210% | ||
| 88 | Enanta Pharmaceuticals Inc | ENTA | 0.200% | ||
| 89 | X4 Pharmaceuticals Inc | XFOR | 0.200% | ||
| 90 | Upstream Bio Inc | UPB | 0.190% | ||
| 91 | Immuneering Corp. | IMRX | 0.170% | ||
| 92 | Inhibikase Thera | IKT | 0.160% | ||
| 93 | Sab Biotherapeutics, Inc. | SABS | 0.150% | ||
| 94 | Sionna Therapeutics Inc | SION | 0.140% | ||
| 95 | Akebia Therapeutics Inc | AKBA | 0.130% | ||
| 96 | Anavex Life Scienc Com New | AVXL | 0.130% | ||
| 97 | Fulcrum Therapeutics Inc Com | FULC | 0.130% | ||
| 98 | Macrogenics Inc | MGNX | 0.130% | ||
| 99 | Bicycle Therapeutics Plc-Adr | BCYC:LN | 0.110% | ||
| 100 | I Mab | IMAB | 0.110% | ||
| 101 | Immunic Inc. | IMUX | 0.110% | ||
| 102 | Protara Therapeutics Inc | TARA | 0.110% | ||
| 103 | Tenax Therapeutics Inc | TENX | 0.030% | ||
| 104 | Contra Chinook Therape | KDNY | 0.000% | ||
| 105 | AstraZeneca PLC | AZN:LN | 0.000% | ||
| 106 | Novo Nordisk A/S | - | 0.000% | ||
| 107 | Cash Equivalent | - | -0.050% |