THNR vs VTI
Amplify Weight Loss Drug & Treatment ETF vs Vanguard Morningstar Total Stock Market ETF
Which is better, THNR or VTI?
VTI has been ahead.
VTI has a lower expense ratio. VTI led over 1Y and the full window. VTI is less concentrated, with 33.3% of the fund in its ten largest positions against 62.0%.
MarketXLS is not an investment adviser. This comparison is generated automatically from market data and is for information only. A Best mark means the better reading on that one measure, not a recommendation to buy.
Side-by-Side Comparison
| Metric | THNR | VTI |
|---|---|---|
| Expense Ratio | 0.59% | 0.03%Best |
| AUM | $6M | $690.1B |
| Dividend Yield | 1.55% | 1.03% |
| Holdings | 45 | 3,524 |
| YTD Return | -2.86% | +12.51%Best |
| 1Y Return | +1.96% | +15.23%Best |
| 3Y Return (annualized) | - | +22.50% |
| 5Y Return (annualized) | - | +12.31% |
| Volatility (annualized) | 15.1% | 11.9%Best |
| Max Drawdown | -33.1% | -19.3%Best |
| $10,000 over 2.4 years | $9,878 | $14,789Best |
| Top 10 Weight | 62.0% | 33.3%Best |
| Fund Family | Amplify ETFs | Vanguard (US) |
| Category | Equity | Equity |
| Style | Large Cap Blend | Large Cap Blend |
| Inception | May 21, 2024 | May 24, 2001 |
Volatility and max drawdown, and the $10,000 over 2.4 years row, are measured over the window both funds cover: May 21, 2024 to Oct 1, 2026 (2.4 years).
THNR vs VTI growth
Month-end closes. Both lines start at 0% in the first month shown, so the gap between them is the difference in growth across that window. The full view covers the 2.4 years both funds cover.
THNR vs VTI Performance
Amplify Weight Loss Drug & Treatment ETF (THNR) is an ETF from Amplify ETFs and Vanguard Morningstar Total Stock Market ETF (VTI) is an ETF from Vanguard (US). Over the past year THNR returned +1.96% while VTI returned +15.23%. Year to date, THNR is down 2.86% versus a gain of 12.51% for VTI.
Past performance does not guarantee future results.
Risk: Volatility and Drawdowns
THNR has been the more volatile fund, with annualized monthly volatility of 15.1% compared with 11.9% for VTI. Lower volatility generally means a smoother ride, though it often comes with lower long-run returns.
The deepest peak-to-trough decline in our data was -33.1% for THNR and -19.3% for VTI. Drawdown depth is what each fund did in the worst stretch of the window measured above.
The two funds' monthly returns correlate at 0.33. They move together some of the time, and apart the rest.
Fees and Cost Over Time
THNR charges 0.59% per year while VTI charges 0.03%. On a $10,000 position that is $59 vs $3 annually, a gap of $56 per year that compounds over a long holding period. On income, THNR currently yields 1.55% against 1.03% for VTI.
Holdings Overlap
57.0% of THNR's money is in holdings VTI also owns. 3.0% of VTI's money is in holdings THNR also owns.
The two portfolios partly overlap.
The two holdings books were reported 46 days apart, THNR as of Sep 15, 2026 and VTI as of Jul 31, 2026, so some of the difference between them is the time between the two reports rather than the funds.
11 positions in common, counted across the 21 positions we hold weights for in THNR and 3,463 in VTI, against full books of 45 and 3,524.
What only one of them owns
Our book lists 1,141 positions for VTI that do not appear in our book for THNR (94.4% of the fund), and 1 for THNR that do not appear in VTI (0.6%).
Some of those will be the same company recorded under a different code in one of the two books, so the real difference in what you would own is no larger than this and may be smaller. We do not name the individual positions here for that reason.
Top Shared Holdings
| Stock | Weight in THNR | Weight in VTI | Difference |
|---|---|---|---|
| LLYEli Lilly & Co. | 8.73% | 1.35% | 7.38% |
| REGNRegeneron Pharmaceuticals, Inc. | 6.20% | 0.11% | 6.09% |
| ABBVAbbvie Inc. | 5.40% | 0.61% | 4.79% |
| MRKMerck & Company Inc | 5.52% | 0.45% | 5.07% |
| AMGNAmgen Inc. | 5.13% | 0.29% | 4.84% |
| SRRKScholar Rock Holding Corporation Com | 5.38% | 0.01% | 5.37% |
| PFEPfizer Inc | 5.05% | 0.20% | 4.85% |
| ARWRArrowhead Pharmaceuticals Inc | 5.02% | 0.02% | 5.00% |
| HIMSHims & Hers Health Inc | 4.63% | 0.01% | 4.62% |
| VKTXViking Therapeutics Inc Com | 4.43% | 0.00% | 4.43% |
57.0% of THNR is already inside VTI.
You probably hold more than these two. Add the rest and see how much of the whole book is the same companies twice.
Free for up to 10 holdings. No account needed.
Frequently Asked Questions
Which is cheaper, THNR or VTI?
THNR has an expense ratio of 0.59% while VTI charges 0.03%. VTI is the cheaper option, by $56 a year on a $10,000 investment.
Which performed better, THNR or VTI?
Over the past year THNR returned +1.96% vs +15.23% for VTI, so VTI leads on 1-year performance. Over the longest common window we track (2 years), THNR annualized -0.51% vs +17.71% for VTI. Past performance does not guarantee future results. This is information, not a recommendation.
Which is riskier, THNR or VTI?
THNR has been the more volatile fund at 15.1% annualized versus 11.9% for VTI. Worst drawdown: THNR -33.1% vs VTI -19.3%.
Should I hold both THNR and VTI?
THNR and VTI have a monthly-return correlation of 0.33, so their returns are far enough apart for the mix to behave differently from either one alone. This is information, not a recommendation.
What is the holdings overlap between THNR and VTI?
57.0% of THNR's money is in holdings VTI also owns. 3.0% of VTI's is in holdings THNR also owns. They hold 11 positions in common, counted across the 21 positions we hold weights for in THNR and 3,463 in VTI.
Which pays a higher dividend, THNR or VTI?
THNR yields 1.55% while VTI yields 1.03%, so THNR currently pays the higher dividend yield.
Is VTI better than THNR?
VTI has a lower expense ratio. VTI led over 1Y and the full window. VTI is less concentrated, with 33.3% of the fund in its ten largest positions against 62.0%. Which one suits a particular account depends on what it is for. This is information, not a recommendation.