HELX ETF largest holding is GH at 9.82% as of Aug 4, 2026
Franklin Genomic Advancements ETF
GH is HELX's largest holding at 9.82% of the fund as of Aug 4, 2026. HELX is Franklin Genomic Advancements ETF.
| # | Ticker | Name | Weight | Cumulative | Shares | Mkt value | Sector | Industry |
|---|---|---|---|---|---|---|---|---|
| 1 |  G | Guardant Health IncHealth Care · Biotechnology | 9.82% | 9.8% | 18,136 | $2.90M | Health Care | Biotechnology |
| 2 |  N | Natera IncHealth Care · Biotechnology | 7.67% | 17.5% | 8,227 | $2.26M | Health Care | Biotechnology |
| Sector and industry · Pro | ||||||||
| 3 |  K | Krystal Biotech Inc | 5.61% | 23.1% | 5,096 | $1.66M | ||
| 4 |  A | Adaptive Biotechnologies Corp | 4.63% | 27.7% | 55,667 | $1.37M | ||
| 5 |  L | Ligand Pharmaceuticals, Inc. | 4.46% | 32.2% | 4,376 | $1.32M | ||
| 6 |  B | Bridgebio Pharma Inc | 3.91% | 36.1% | 14,066 | $1.15M | ||
| 7 |  U | United Therapeutics Corp | 3.41% | 39.5% | 1,938 | $1.01M | ||
| 8 |  L | Eli Lilly & Co. | 2.88% | 42.4% | 762 | $850.1K | ||
| 9 |  T | Twist Bioscience Corp. | 2.79% | 45.2% | 8,288 | $824.2K | ||
| 10 | — | Nvaesrtex Pharmaceuticals Inc | 2.68% | 47.9% | 1,655 | $792.3K | ||
| 11 | — | Samsung Biologics Co Ltd | 2.63% | 50.5% | 752 | $775.2K | ||
| 12 |  C | Corteva Inc Ctva | 2.60% | 53.1% | 9,800 | $767.4K | ||
| 13 |  T | Travere Therapeutics Inc | 2.59% | 55.7% | 13,663 | $765.4K | ||
| 14 |  M | Medpace Holdings Inc | 2.36% | 58.0% | 1,213 | $697.6K | ||
| 15 | — | AstraZeneca PLC | 2.25% | 60.3% | 4,263 | $663.4K | ||
| 16 |  R | Regeneron Pharmaceuticals, Inc. | 2.22% | 62.5% | 862 | $655.7K | ||
| 17 |  N | Neurocrine Biosciences Inc | 1.84% | 64.3% | 3,276 | $544.0K | ||
| 18 | — | Argenx Se | 1.50% | 65.8% | 529 | $443.8K | ||
| 19 |  V | Veracyte Inc | 1.47% | 67.3% | 9,340 | $433.5K | ||
| 20 | — | Tempus Pe | 1.40% | 68.7% | 8,774 | $412.8K | ||
| 21 |  C | Caredx Inc | 1.37% | 70.1% | 8,571 | $403.6K | ||
| 22 |  C | Charles River Laboratories International Inc | 1.32% | 71.4% | 1,667 | $390.3K | ||
| 23 |  S | Stoke Therapeuti | 1.30% | 72.7% | 12,159 | $385.1K | ||
| 24 |  P | Ptc Therapeutics Inc | 1.26% | 74.0% | 5,366 | $370.8K | ||
| 25 |  J | Jazz Pharmaceuticals Plc. | 1.23% | 75.2% | 1,389 | $363.4K | ||
| 26 | — | Biontech Se Adr | 1.22% | 76.4% | 3,927 | $358.7K | ||
| 27 |  P | Praxis Precision Medicines, Inc. | 1.21% | 77.6% | 1,147 | $355.6K | ||
| 28 |  G | Grail Inc Common Stock Usd | 1.18% | 78.8% | 4,774 | $347.1K | ||
| 29 |  R | Repligen Corp | 1.09% | 79.9% | 2,152 | $322.3K | ||
| 30 |  R | Revolution Medicines Inc | 1.01% | 80.9% | 1,544 | $298.7K | ||
| 31 |  I | Iqvia Holdings Inc | 1.00% | 81.9% | 1,290 | $294.4K | ||
| 32 | — | Crispr Therapeutics Ag Common Shares | 0.97% | 82.9% | 5,389 | $286.0K | ||
| 33 |  I | Insmed Inc | 0.91% | 83.8% | 2,728 | $269.4K | ||
| 34 |  C | Cadence Design Systems Inc. | 0.90% | 84.7% | 776 | $264.3K | ||
| 35 |  A | Anaptysbio Inc | 0.86% | 85.6% | 4,596 | $253.4K | ||
| 36 | — | Sartorius Ag Vorzug | 0.86% | 86.4% | 969 | $254.1K | ||
| 37 |  T | Thermo Fisherscientific Inc. | 0.86% | 87.3% | 451 | $254.7K | ||
| 38 |  T | First Tracks Biotherapeutics, Inc. | 0.79% | 88.1% | 5,045 | $232.1K | ||
| 39 |  B | Beam Therapeutics Inc | 0.78% | 88.8% | 8,118 | $230.1K | ||
| 40 |  A | Axsome Therapeutics, Inc. | 0.72% | 89.6% | 1,002 | $212.6K | ||
| 41 |  H | Hinge Health Inc Ordinary Shares - Class A | 0.68% | 90.2% | 2,516 | $199.8K | ||
| 42 |  A | Agilent Technologies Inc | 0.62% | 90.9% | 1,310 | $182.4K | ||
| 43 |  D | Danaher Corp | 0.60% | 91.5% | 902 | $175.7K | ||
| 44 |  C | Cogent Biosciences Inc | 0.53% | 92.0% | 3,670 | $157.2K | ||
| 45 |  Q | Qiagen N.V. | 0.53% | 92.5% | 3,663 | $155.1K | ||
| 46 |  C | Celcuity Inc | 0.51% | 93.0% | 1,623 | $150.1K | ||
| 47 | — | Genmab A/s ADR | 0.50% | 93.5% | 5,120 | $148.6K | ||
| 48 |  M | Mineralys Therapeutics Inc | 0.49% | 94.0% | 5,443 | $144.2K | ||
| 49 |  A | Alnylam Pharmaceuticals Inc. | 0.48% | 94.5% | 653 | $143.0K | ||
| 50 |  R | Ultragenyx Pharmaceutical Inc | 0.48% | 95.0% | 5,497 | $141.9K | ||
| More holdings · Pro | ||||||||
HELX ETF All Holdings
HELX holdings total 65 positions. The top 10 holdings account for 47.9% of the fund, led by Guardant Health Inc at 9.8%, Natera Inc at 7.7%, Krystal Biotech Inc at 5.6%.
HELX portfolio concentration is moderate, with the top 10 representing 47.9% of total assets. The largest sector exposure is Health Care at 84.2%.
HELX sectors provide a detailed breakdown. HELX overlap shows how holdings compare to other funds in your portfolio.
HELX ETF Holdings
69 of 65 holdings
- 1
Guardant Health Inc
GHHealth Care9.82% - 2
Natera Inc
NTRAHealth Care7.67% - 3
Krystal Biotech Inc
KRYSHealth Care5.61% - 4
Adaptive Biotechnologies Corp
ADPTHealth Care4.63% - 5
Ligand Pharmaceuticals, Inc.
LGNDHealth Care4.46% - 6
Bridgebio Pharma Inc
BBIOHealth Care3.91% - 7
United Therapeutics Corp
UTHRHealth Care3.41% - 8
Eli Lilly & Co.
LLYHealth Care2.88% - 9
Twist Bioscience Corp.
TWSTHealth Care2.79% - 10
Nvaesrtex Pharmaceuticals Inc
VRTXHealth Care2.68% - 11
Samsung Biologics Co Ltd
207940:KRUnknown2.63% - 12
Corteva Inc Ctva
CTVAMaterials2.60% - 13
Travere Therapeutics Inc
TVTXHealth Care2.59% - 14
Medpace Holdings Inc
MEDPHealth Care2.36% - 15
AstraZeneca PLC
AZN:LNUnknown2.25% - 16
Regeneron Pharmaceuticals, Inc.
REGNHealth Care2.22% - 17
Neurocrine Biosciences Inc
NBIXHealth Care1.84% - 18
Argenx Se
ARGX:ASUnknown1.50% - 19
Veracyte Inc
VCYTHealth Care1.47% - 20
Tempus Pe
TEMInformation Technology1.40% - 21
Caredx Inc
CDNAHealth Care1.37% - 22
Charles River Laboratories International Inc
CRLHealth Care1.32% - 23
Stoke Therapeuti
STOKHealth Care1.30% - 24
Ptc Therapeutics Inc
PTCTHealth Care1.26% - 25
Jazz Pharmaceuticals Plc.
JAZZHealth Care1.23% - 26
Biontech Se Adr
BNTX:FFHealth Care1.22% - 27
Praxis Precision Medicines, Inc.
PRAXHealth Care1.21% - 28
Grail Inc Common Stock Usd
GRALHealth Care1.18% - 29
Repligen Corp
RGENHealth Care1.09% - 30
Revolution Medicines Inc
RVMDHealth Care1.01% - 31
Iqvia Holdings Inc
IQVHealth Care1.00% - 32
Crispr Therapeutics Ag Common Shares
CRSP:SMHealth Care0.97% - 33
Insmed Inc
INSMHealth Care0.91% - 34
Cadence Design Systems Inc.
CDNSInformation Technology0.90% - 35
Anaptysbio Inc
ANABHealth Care0.86% - 36
Sartorius Ag Vorzug
SRT3:SGHealth Care0.86% - 37
Thermo Fisherscientific Inc.
TMOHealth Care0.86% - 38
First Tracks Biotherapeutics, Inc.
TRAXUnknown0.79% - 39
Beam Therapeutics Inc
BEAMHealth Care0.78% - 40
Axsome Therapeutics, Inc.
AXSMHealth Care0.72% - 41
Hinge Health Inc Ordinary Shares - Class A
HNGEFinancials0.68% - 42
Agilent Technologies Inc
AInformation Technology0.62% - 43
Danaher Corporation
DHRHealth Care0.60% - 44
Cogent Biosciences Inc
COGTHealth Care0.53% - 45
Qiagen N.V.
QIA:ASUnknown0.53% - 46
Celcuity Inc Com
CELCHealth Care0.51% - 47
Genmab A/s ADR
GMAB:COHealth Care0.50% - 48
Mineralys Therapeutics Inc
MLYSHealth Care0.49% - 49
Alnylam Pharmaceuticals Inc.
ALNYHealth Care0.48% - 50
Ultragenyx Pharmaceutical Inc
RAREHealth Care0.48% - 51
Roivant Sciences Ltd. Common Shares
ROIV:BMHealth Care0.48% - 52
Veradermics Inc
MANEUnknown0.46% - 53
Arcutis Biotherapeutics Inc
ARQTHealth Care0.42% - 54
Constellation En Gen Llc Sr Unsecured 06/29 4.55
Other0.42% - 55
Kiniksa Pharmaceuticals Inte
KNSA:LNUnknown0.41% - 56
Rhythm Pharmaceuticals Inc
RYTMHealth Care0.40% - 57
Bristol-Myers Squibb Co.
BMYHealth Care0.39% - 58
Bio-Rad Laboratories-A Common Stock
BIOHealth Care0.29% - 59
Liquidia Technologies Inc
LQDAHealth Care0.28% - 60
Beigene Limited, ADR
688235:SHUnknown0.26% - 61
Tarsus Pharmaceuticals Inc
TARSHealth Care0.25% - 62
NEURogene
NGNEUnknown0.25% - 63
Ionis Pharmaceuticals Inc
IONSHealth Care0.22% - 64
Tg Therapeutics Inc Common Stock
TGTXHealth Care0.22% - 65
Samsung Epis Holdings Co Ltd
0126Z0:KRUnknown0.16% - 66
Genedx Holdings Corp
WGSHealth Care0.15% - 67
Omniab, Inc.
OABIHealth Care0.00% - 68
Omniab Inc - 12.5 Earnout
OABIUnknown0.00% - 69
Net Current Assets
Other-0.05%
| # | Company | Ticker | Sector | Industry | Weight |
|---|---|---|---|---|---|
| 1 | Guardant Health Inc | GH | 9.820% | ||
| 2 | Natera Inc | NTRA | 7.670% | ||
| 3 | Krystal Biotech Inc | KRYS | 5.610% | ||
| 4 | Adaptive Biotechnologies Corp | ADPT | 4.630% | ||
| 5 | Ligand Pharmaceuticals, Inc. | LGND | 4.460% | ||
| 6 | Bridgebio Pharma Inc | BBIO | 3.910% | ||
| 7 | United Therapeutics Corp | UTHR | 3.410% | ||
| 8 | Eli Lilly & Co. | LLY | 2.880% | ||
| 9 | Twist Bioscience Corp. | TWST | 2.790% | ||
| 10 | Nvaesrtex Pharmaceuticals Inc | VRTX | 2.680% | ||
| 11 | Samsung Biologics Co Ltd | 207940:KR | 2.630% | ||
| 12 | Corteva Inc Ctva | CTVA | 2.600% | ||
| 13 | Travere Therapeutics Inc | TVTX | 2.590% | ||
| 14 | Medpace Holdings Inc | MEDP | 2.360% | ||
| 15 | AstraZeneca PLC | AZN:LN | 2.250% | ||
| 16 | Regeneron Pharmaceuticals, Inc. | REGN | 2.220% | ||
| 17 | Neurocrine Biosciences Inc | NBIX | 1.840% | ||
| 18 | Argenx Se | ARGX:AS | 1.500% | ||
| 19 | Veracyte Inc | VCYT | 1.470% | ||
| 20 | Tempus Pe | TEM | 1.400% | ||
| 21 | Caredx Inc | CDNA | 1.370% | ||
| 22 | Charles River Laboratories International Inc | CRL | 1.320% | ||
| 23 | Stoke Therapeuti | STOK | 1.300% | ||
| 24 | Ptc Therapeutics Inc | PTCT | 1.260% | ||
| 25 | Jazz Pharmaceuticals Plc. | JAZZ | 1.230% | ||
| 26 | Biontech Se Adr | BNTX:FF | 1.220% | ||
| 27 | Praxis Precision Medicines, Inc. | PRAX | 1.210% | ||
| 28 | Grail Inc Common Stock Usd | GRAL | 1.180% | ||
| 29 | Repligen Corp | RGEN | 1.090% | ||
| 30 | Revolution Medicines Inc | RVMD | 1.010% | ||
| 31 | Iqvia Holdings Inc | IQV | 1.000% | ||
| 32 | Crispr Therapeutics Ag Common Shares | CRSP:SM | 0.970% | ||
| 33 | Insmed Inc | INSM | 0.910% | ||
| 34 | Cadence Design Systems Inc. | CDNS | 0.900% | ||
| 35 | Anaptysbio Inc | ANAB | 0.860% | ||
| 36 | Sartorius Ag Vorzug | SRT3:SG | 0.860% | ||
| 37 | Thermo Fisherscientific Inc. | TMO | 0.860% | ||
| 38 | First Tracks Biotherapeutics, Inc. | TRAX | 0.790% | ||
| 39 | Beam Therapeutics Inc | BEAM | 0.780% | ||
| 40 | Axsome Therapeutics, Inc. | AXSM | 0.720% | ||
| 41 | Hinge Health Inc Ordinary Shares - Class A | HNGE | 0.680% | ||
| 42 | Agilent Technologies Inc | A | 0.620% | ||
| 43 | Danaher Corporation | DHR | 0.600% | ||
| 44 | Cogent Biosciences Inc | COGT | 0.530% | ||
| 45 | Qiagen N.V. | QIA:AS | 0.530% | ||
| 46 | Celcuity Inc Com | CELC | 0.510% | ||
| 47 | Genmab A/s ADR | GMAB:CO | 0.500% | ||
| 48 | Mineralys Therapeutics Inc | MLYS | 0.490% | ||
| 49 | Alnylam Pharmaceuticals Inc. | ALNY | 0.480% | ||
| 50 | Ultragenyx Pharmaceutical Inc | RARE | 0.480% | ||
| 51 | Roivant Sciences Ltd. Common Shares | ROIV:BM | 0.480% | ||
| 52 | Veradermics Inc | MANE | 0.460% | ||
| 53 | Arcutis Biotherapeutics Inc | ARQT | 0.420% | ||
| 54 | Constellation En Gen Llc Sr Unsecured 06/29 4.55 | - | 0.420% | ||
| 55 | Kiniksa Pharmaceuticals Inte | KNSA:LN | 0.410% | ||
| 56 | Rhythm Pharmaceuticals Inc | RYTM | 0.400% | ||
| 57 | Bristol-Myers Squibb Co. | BMY | 0.390% | ||
| 58 | Bio-Rad Laboratories-A Common Stock | BIO | 0.290% | ||
| 59 | Liquidia Technologies Inc | LQDA | 0.280% | ||
| 60 | Beigene Limited, ADR | 688235:SH | 0.260% | ||
| 61 | Tarsus Pharmaceuticals Inc | TARS | 0.250% | ||
| 62 | NEURogene | NGNE | 0.250% | ||
| 63 | Ionis Pharmaceuticals Inc | IONS | 0.220% | ||
| 64 | Tg Therapeutics Inc Common Stock | TGTX | 0.220% | ||
| 65 | Samsung Epis Holdings Co Ltd | 0126Z0:KR | 0.160% | ||
| 66 | Genedx Holdings Corp | WGS | 0.150% | ||
| 67 | Omniab, Inc. | OABI | 0.000% | ||
| 68 | Omniab Inc - 12.5 Earnout | OABI | 0.000% | ||
| 69 | Net Current Assets | - | -0.050% |