HELX ETF

$43.53

AUM$33M

TER0.50%

Holdings70

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HELX ETF

$43.53

Franklin Genomic Advancements ETF

AUM$33M

TER0.50%

Holdings70

See how much of HELX you already own

Just $25 once·$99/mo·Download sample

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Overview Performance Chart Dividends Top Holdings All Holdings Sectors Geography Similar Compare Overlap

GH is HELX's largest holding at 9.29% of the fund as of Sep 15, 2026. HELX is Franklin Genomic Advancements ETF.

Showing top 50 of 70 holdings · as of Sep 15, 2026

HELX holdings, by weight
#	Ticker	Name	Weight	Cumulative	Shares	Mkt value	Sector	Industry
1	GH	Guardant Health, IncHealth Care · Biotechnology	9.29%	9.3%	18,136	$2.85M	Health Care	Biotechnology
2	NTRA	Natera IncHealth Care · Biotechnology	8.81%	18.1%	8,227	$2.71M	Health Care	Biotechnology
Sector and industry · Pro
3	KRYS	Krystal Biotech Inc	5.75%	23.9%	5,096	$1.77M
4	LGND	Ligand Pharmaceuticals, Inc.	4.41%	28.3%	4,768	$1.36M
5	ADPT	Adaptive Biotechnologies Corp	4.38%	32.6%	55,667	$1.35M
6	TWST	Twist Bioscience Corp.	3.75%	36.4%	9,069	$1.15M
7	BBIO	Bridgebio Pharma Inc_None_0	3.32%	39.7%	14,066	$1.02M
8	TVTX	Travere Therapeutics Inc	3.26%	43.0%	15,153	$1.00M
9	—	Nvaesrtex Pharmaceuticals Inc	2.78%	45.8%	1,655	$853.1K
10	MEDP	Medpace Holdings Inc	2.71%	48.5%	1,415	$831.3K
11	CTVA	Corteva Inc Ctva	2.68%	51.1%	9,800	$822.2K
12	UTHR	United Therapeutics Corp	2.48%	53.6%	1,532	$761.6K
13	LLY	Eli Lilly & Co.	2.33%	55.9%	643	$717.4K
14	REGN	Regeneron Pharmaceuticals, Inc.	2.19%	58.1%	862	$673.6K
15	RGEN	Repligen Corp	1.92%	60.1%	3,569	$589.5K
16	—	Argenx	1.71%	61.8%	529	$524.6K
17	—	Tempus Pe	1.68%	63.4%	8,774	$517.8K
18	NBIX	Neurocrine Biosciences Inc	1.67%	65.1%	3,276	$511.8K
19	JAZZ	Jazz Pharmaceuticals Plc.	1.52%	66.6%	1,895	$465.8K
20	CRL	Charles River Laboratories International Inc	1.51%	68.1%	1,667	$463.9K
21	CDNA	Caredx Inc	1.40%	69.5%	8,571	$430.8K
22	PRAX	Praxis Precision Medicines, Inc.	1.25%	70.8%	1,147	$383.8K
23	—	Biontech Se Adr	1.24%	72.0%	3,927	$379.9K
24	GRAL	Grail, Inc.	1.18%	73.2%	4,774	$363.9K
25	INSM	Insmed Inc	1.15%	74.4%	2,728	$353.0K
26	PTCT	Ptc Therapeutics Inc	1.15%	75.5%	5,366	$354.5K
27	STOK	Stoke Therapeutics Inc	1.15%	76.7%	12,159	$353.0K
28	TXG	10x Genomics Inc Com Usd 1 Cl A	1.12%	77.8%	5,017	$344.1K
29	IQV	Iqvia Holdings Inc	1.10%	78.9%	1,290	$337.7K
30	RVMD	Revolution Medicines Inc	1.02%	79.9%	1,544	$314.6K
31	RPRX	Royalty Pharma Plc Class A Ordinary Share	1.01%	80.9%	5,276	$309.2K
32	—	Kiniksa Pharmaceuticals, Ltd.	1.00%	81.9%	4,016	$306.3K
33	—	Samsung Biologics Co Ltd	0.98%	82.9%	285	$299.7K
34	VCYT	Veracyte, Inc.	0.97%	83.9%	7,289	$297.9K
35	—	Crispr Therapeutics Ag Common Shares	0.91%	84.8%	5,389	$278.7K
36	TMO	Thermo Fisherscientific Inc.	0.90%	85.7%	451	$275.0K
37	HNGE	Hinge Health Inc	0.87%	86.6%	3,017	$267.3K
38	—	Sartorius Ag Vorzug	0.85%	87.4%	969	$262.1K
39	ANAB	Anaptysbio Inc	0.81%	88.2%	4,596	$247.6K
40	ETON	Eton Pharmaceuticals Inc.	0.74%	89.0%	3,963	$226.2K
41	AXSM	Axsome Therapeutics Inc	0.72%	89.7%	1,002	$221.2K
42	CDNS	Cadence Design Systems Inc.	0.65%	90.3%	690	$199.7K
43	A	Agilent Technologies Inc	0.63%	91.0%	1,310	$192.5K
44	BEAM	Beam Therapeutics Inc.	0.63%	91.6%	8,118	$194.8K
45	TRAX	First Tracks Biotherapeutics, Inc.	0.60%	92.2%	5,045	$183.8K
46	—	Roivant Sciences Ltd. Common Shares	0.55%	92.7%	4,134	$168.7K
47	—	Genmab A/s ADR	0.54%	93.3%	5,120	$166.2K
48	TGTX	Tg Therapeutics Inc	0.51%	93.8%	2,928	$157.8K
49	—	AstraZeneca PLC	0.51%	94.3%	975	$156.2K
50	QGEN	Qiagen N.V.	0.51%	94.8%	3,663	$155.7K
More holdings · Pro

Not reported for this fund: share changes.

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HELX ETF All Holdings

HELX holdings total 70 positions. The top 10 holdings account for 48.5% of the fund, led by Guardant Health, Inc at 9.3%, Natera Inc at 8.8%, Krystal Biotech Inc at 5.8%.

HELX portfolio concentration is moderate, with the top 10 representing 48.5% of total assets. The largest sector exposure is Health Care at 86.1%.

HELX sectors provide a detailed breakdown. HELX overlap shows how holdings compare to other funds in your portfolio.

Compare HELX

HELX vs SPY HELX vs QQQ HELX vs VOO HELX vs VTI HELX vs IVV HELX vs SCHD HELX vs VYM HELX vs VXUS

HELX ETF Holdings

70 of 70 holdings

Sector

Industry

Sort By

1
Guardant Health, Inc
GHHealth Care
9.29%
2
Natera Inc
NTRAHealth Care
8.81%
3
Krystal Biotech Inc
KRYSHealth Care
5.75%
4
Ligand Pharmaceuticals, Inc.
LGNDHealth Care
4.41%
5
Adaptive Biotechnologies Corp
ADPTHealth Care
4.38%
6
Twist Bioscience Corp.
TWSTHealth Care
3.75%
7
Bridgebio Pharma Inc_None_0
BBIOHealth Care
3.32%
8
Travere Therapeutics Inc
TVTXHealth Care
3.26%
9
Nvaesrtex Pharmaceuticals Inc
VRTXHealth Care
2.78%
10
Medpace Holdings Inc
MEDPHealth Care
2.71%
11
Corteva Inc Ctva
CTVAMaterials
2.68%
12
United Therapeutics Corp
UTHRHealth Care
2.48%
13
Eli Lilly & Co.
LLYHealth Care
2.33%
14
Regeneron Pharmaceuticals, Inc.
REGNHealth Care
2.19%
15
Repligen Corp
RGENHealth Care
1.92%
16
Argenx
ARGX:ASUnknown
1.71%
17
Tempus Pe
TEMInformation Technology
1.68%
18
Neurocrine Biosciences Inc
NBIXHealth Care
1.67%
19
Jazz Pharmaceuticals Plc.
JAZZHealth Care
1.52%
20
Charles River Laboratories International Inc
CRLHealth Care
1.51%
21
Caredx Inc
CDNAHealth Care
1.40%
22
Praxis Precision Medicines, Inc.
PRAXHealth Care
1.25%
23
Biontech Se Adr
BNTX:FFHealth Care
1.24%
24
Grail, Inc.
GRALHealth Care
1.18%
25
Insmed Inc
INSMHealth Care
1.15%
26
Ptc Therapeutics Inc
PTCTHealth Care
1.15%
27
Stoke Therapeutics Inc Com
STOKHealth Care
1.15%
28
10x Genomics Inc Com Usd 1 Cl A
TXGHealth Care
1.12%
29
Iqvia Holdings Inc
IQVHealth Care
1.10%
30
Revolution Medicines Inc
RVMDHealth Care
1.02%
31
Royalty Pharma Plc Class A Ordinary Share
RPD:DUFinancials
1.01%
32
Kiniksa Pharmaceuticals, Ltd.
KNSA:LNUnknown
1.00%
33
Samsung Biologics Co Ltd
207940:KRUnknown
0.98%
34
Veracyte, Inc.
VCYTHealth Care
0.97%
35
Crispr Therapeutics Ag Common Shares
CRSP:SMHealth Care
0.91%
36
Thermo Fisherscientific Inc.
TMOHealth Care
0.90%
37
Hinge Health Inc
HNGEFinancials
0.87%
38
Sartorius Ag Vorzug
SRT3:SGHealth Care
0.85%
39
Anaptysbio Inc
ANABHealth Care
0.81%
40
Eton Pharmaceuticals Inc.
ETONHealth Care
0.74%
41
Axsome Therapeutics Inc
AXSMHealth Care
0.72%
42
Cadence Design Systems Inc.
CDNSInformation Technology
0.65%
43
Agilent Technologies Inc
AInformation Technology
0.63%
44
Beam Therapeutics Inc. Com
BEAMHealth Care
0.63%
45
First Tracks Biotherapeutics, Inc.
TRAXUnknown
0.60%
46
Roivant Sciences Ltd. Common Shares
ROIV:BMHealth Care
0.55%
47
Genmab A/s ADR
GMAB:COHealth Care
0.54%
48
Tg Therapeutics Inc Common Stock
TGTXHealth Care
0.51%
49
AstraZeneca PLC
AZN:LNUnknown
0.51%
50
Qiagen N.V.
QIA:ASUnknown
0.51%
51
Mineralys Therapeutics Inc
MLYSHealth Care
0.50%
52
Moderna therapeutics
MRNAHealth Care
0.49%
53
Glaukos Corp.
GKOSHealth Care
0.47%
54
Celcuity Inc Com
CELCHealth Care
0.44%
55
Veradermics Inc
MANEUnknown
0.41%
56
Cogent Biosciences Inc
COGTHealth Care
0.40%
57
Rhythm Pharmaceuticals Inc
RYTMHealth Care
0.38%
58
Arcutis Biotherapeutics Inc
ARQTHealth Care
0.37%
59
Bio-Rad Laboratories-A Common Stock
BIOHealth Care
0.31%
60
Tarsus Pharmaceuticals Inc
TARSHealth Care
0.31%
61
Beone Medicines Ltd
ONC:SMUnknown
0.27%
62
NEURogene
NGNEUnknown
0.24%
63
Liquidia Technologies Inc
LQDAHealth Care
0.20%
64
Genedx Holdings Corp
WGSHealth Care
0.17%
65
Samsung Episholdings Co L
0126Z0:KRUnknown
0.14%
66
Ultragenyx Pharmaceutical Inc
RAREHealth Care
0.07%
67
Cash
Other
0.06%
68
Omniab Inc 12.5 Earnout
OABIHealth Care
0.00%
69
Omniab Inc 15.00 Earnout
OABIHealth Care
0.00%
70
Net Current Assets
Other
-0.01%

#	Company	Ticker	Weight
1	Guardant Health, Inc	GH	9.290%
2	Natera Inc	NTRA	8.810%
3	Krystal Biotech Inc	KRYS	5.750%
4	Ligand Pharmaceuticals, Inc.	LGND	4.410%
5	Adaptive Biotechnologies Corp	ADPT	4.380%
6	Twist Bioscience Corp.	TWST	3.750%
7	Bridgebio Pharma Inc_None_0	BBIO	3.320%
8	Travere Therapeutics Inc	TVTX	3.260%
9	Nvaesrtex Pharmaceuticals Inc	VRTX	2.780%
10	Medpace Holdings Inc	MEDP	2.710%
11	Corteva Inc Ctva	CTVA	2.680%
12	United Therapeutics Corp	UTHR	2.480%
13	Eli Lilly & Co.	LLY	2.330%
14	Regeneron Pharmaceuticals, Inc.	REGN	2.190%
15	Repligen Corp	RGEN	1.920%
16	Argenx	ARGX:AS	1.710%
17	Tempus Pe	TEM	1.680%
18	Neurocrine Biosciences Inc	NBIX	1.670%
19	Jazz Pharmaceuticals Plc.	JAZZ	1.520%
20	Charles River Laboratories International Inc	CRL	1.510%
21	Caredx Inc	CDNA	1.400%
22	Praxis Precision Medicines, Inc.	PRAX	1.250%
23	Biontech Se Adr	BNTX:FF	1.240%
24	Grail, Inc.	GRAL	1.180%
25	Insmed Inc	INSM	1.150%
26	Ptc Therapeutics Inc	PTCT	1.150%
27	Stoke Therapeutics Inc Com	STOK	1.150%
28	10x Genomics Inc Com Usd 1 Cl A	TXG	1.120%
29	Iqvia Holdings Inc	IQV	1.100%
30	Revolution Medicines Inc	RVMD	1.020%
31	Royalty Pharma Plc Class A Ordinary Share	RPD:DU	1.010%
32	Kiniksa Pharmaceuticals, Ltd.	KNSA:LN	1.000%
33	Samsung Biologics Co Ltd	207940:KR	0.980%
34	Veracyte, Inc.	VCYT	0.970%
35	Crispr Therapeutics Ag Common Shares	CRSP:SM	0.910%
36	Thermo Fisherscientific Inc.	TMO	0.900%
37	Hinge Health Inc	HNGE	0.870%
38	Sartorius Ag Vorzug	SRT3:SG	0.850%
39	Anaptysbio Inc	ANAB	0.810%
40	Eton Pharmaceuticals Inc.	ETON	0.740%
41	Axsome Therapeutics Inc	AXSM	0.720%
42	Cadence Design Systems Inc.	CDNS	0.650%
43	Agilent Technologies Inc	A	0.630%
44	Beam Therapeutics Inc. Com	BEAM	0.630%
45	First Tracks Biotherapeutics, Inc.	TRAX	0.600%
46	Roivant Sciences Ltd. Common Shares	ROIV:BM	0.550%
47	Genmab A/s ADR	GMAB:CO	0.540%
48	Tg Therapeutics Inc Common Stock	TGTX	0.510%
49	AstraZeneca PLC	AZN:LN	0.510%
50	Qiagen N.V.	QIA:AS	0.510%
51	Mineralys Therapeutics Inc	MLYS	0.500%
52	Moderna therapeutics	MRNA	0.490%
53	Glaukos Corp.	GKOS	0.470%
54	Celcuity Inc Com	CELC	0.440%
55	Veradermics Inc	MANE	0.410%
56	Cogent Biosciences Inc	COGT	0.400%
57	Rhythm Pharmaceuticals Inc	RYTM	0.380%
58	Arcutis Biotherapeutics Inc	ARQT	0.370%
59	Bio-Rad Laboratories-A Common Stock	BIO	0.310%
60	Tarsus Pharmaceuticals Inc	TARS	0.310%
61	Beone Medicines Ltd	ONC:SM	0.270%
62	NEURogene	NGNE	0.240%
63	Liquidia Technologies Inc	LQDA	0.200%
64	Genedx Holdings Corp	WGS	0.170%
65	Samsung Episholdings Co L	0126Z0:KR	0.140%
66	Ultragenyx Pharmaceutical Inc	RARE	0.070%
67	Cash	-	0.060%
68	Omniab Inc 12.5 Earnout	OABI	0.000%
69	Omniab Inc 15.00 Earnout	OABI	0.000%
70	Net Current Assets	-	-0.010%