PBE ETF largest holding is REGN at 5.33% as of Aug 5, 2026

PBE ETF largest holding is REGN at 5.33% as of Aug 5, 2026
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REGN is PBE's largest holding at 5.33% of the fund as of Aug 5, 2026. PBE is Invesco Biotechnology and Genome ETF.

Showing top 34 of 34 holdings · as of Aug 5, 2026
PBE holdings, by weight
#TickerNameWeightCumulativeSharesMkt valueSectorIndustry
1
REGN
Regeneron Pharmaceuticals, Inc.Health Care · Pharmaceuticals
5.33%		5.3%24,329$18.51MHealth CarePharmaceuticals
2
CDNA
Caredx IncHealth Care · Healthcare Services
5.31%		10.6%391,227$18.42MHealth CareHealthcare Services
Share changes, sector and industry · Pro
3
AMGN
Amgen Inc.
5.17%		15.8%45,967$17.93M
4—Nvaesrtex Pharmaceuticals Inc
4.89%		20.7%35,476$16.98M
5
BIIB
Biogen Inc.
4.81%		25.5%80,011$16.68M
6
RPRX
Royalty Pharma Plc Class A Ordinary Share
4.75%		30.3%286,870$16.49M
7
GILD
Gilead Sciences
4.50%		34.8%115,546$15.63M
8
UTHR
United Therapeutics Corp
3.99%		38.8%26,677$13.84M
9
TECH
Bio-Techne Corp
3.65%		42.4%175,715$12.67M
10
ILMN
Illumina, Inc.
3.39%		45.8%58,023$11.78M
11
ALNY
Alnylam Pharmaceuticals Inc.
3.30%		49.1%52,289$11.45M
12
PTGX
Protagonist Therapeutics Inc
3.30%		52.4%84,263$11.44M
13
VCEL
Vericel Corp
3.22%		55.6%241,002$11.17M
14
RGEN
Repligen Corp
3.16%		58.8%73,159$10.96M
15
ACAD
Acadia Pharmaceuticals Inc
3.10%		61.9%396,408$10.76M
16
INCY
Incyte Corp.
3.02%		64.9%86,792$10.47M
17
HALO
Halozyme Therapeutics Inc
2.94%		67.8%122,665$10.21M
18—Qiagen Nv
2.89%		70.7%237,151$10.04M
19
BMRN
Biomarin Pharmaceutical Inc.
2.79%		73.5%159,405$9.68M
20
EXEL
Exelixis Inc
2.72%		76.2%168,624$9.44M
21
OMER
Omeros Corp
2.70%		78.9%723,413$9.36M
22
BCRX
BioCryst Pharmaceuticals Inc.
2.59%		81.5%994,963$8.97M
23
NBIX
Neurocrine Biosciences Inc
2.59%		84.1%54,131$8.99M
24
COLL
Collegium Pharmaceutical Inc
2.57%		86.7%249,464$8.91M
25
VCYT
Veracyte, Inc.
2.55%		89.2%190,627$8.85M
26
PTCT
Ptc Therapeutics Inc
2.48%		91.7%124,597$8.61M
27
SRPT
Sarepta Therapeutics Inc
2.39%		94.1%505,556$8.29M
28
ANAB
Anaptysbio Inc
2.32%		96.4%145,887$8.04M
29
ARDX
Ardelyx Inc
1.95%		98.4%1,348,416$6.76M
30
LEGN
Legend Biotech, Adr
1.57%		99.9%285,388$5.46M
31
AGPXX
Invesco Government & Agency Portfolio, Institutional Class
0.06%		100.0%203,108$203.1K
32DebtCommonwealth Of Massachusetts
0.00%		100.0%-$63
33—Essex Portfolio Lp Company Guar 01/31 1.65
0.00%		100.0%1-
34DebtCigna Group/The Sr Unsecured 05/29 5
0.00%		100.0%5,727$5.7K
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PBE ETF All Holdings

PBE holdings total 33 positions. The top 10 holdings account for 45.8% of the fund, led by Regeneron Pharmaceuticals, Inc. at 5.3%, Caredx Inc at 5.3%, Amgen Inc. at 5.2%.

PBE portfolio concentration is moderate, with the top 10 representing 45.8% of total assets. The largest sector exposure is Health Care at 92.3%.

PBE sectors provide a detailed breakdown. PBE overlap shows how holdings compare to other funds in your portfolio.

Compare PBE

PBE vs SPYPBE vs QQQPBE vs VOOPBE vs VTIPBE vs IVVPBE vs SCHDPBE vs VYMPBE vs VXUS

PBE ETF Holdings

34 of 33 holdings

  • 1

    Regeneron Pharmaceuticals, Inc.

    REGNHealth Care
    5.33%
  • 2

    Caredx Inc

    CDNAHealth Care
    5.31%
  • 3

    Amgen Inc.

    AMGNHealth Care
    5.17%
  • 4

    Nvaesrtex Pharmaceuticals Inc

    VRTXHealth Care
    4.89%
  • 5

    Biogen Inc. Com

    BIIBHealth Care
    4.81%
  • 6

    Royalty Pharma Plc Class A Ordinary Share

    RPD:DUFinancials
    4.75%
  • 7

    Gilead Sciences

    GILDHealth Care
    4.50%
  • 8

    United Therapeutics Corp

    UTHRHealth Care
    3.99%
  • 9

    Bio-Techne Corp

    TECHHealth Care
    3.65%
  • 10

    Illumina, Inc.

    ILMNHealth Care
    3.39%
  • 11

    Alnylam Pharmaceuticals Inc.

    ALNYHealth Care
    3.30%
  • 12

    Protagonist Therapeutics Inc

    PTGXHealth Care
    3.30%
  • 13

    Vericel Corp

    VCELHealth Care
    3.22%
  • 14

    Repligen Corp

    RGENHealth Care
    3.16%
  • 15

    Acadia Pharmaceuticals Inc Common Stock Usd 0.0001

    ACADHealth Care
    3.10%
  • 16

    Incyte Corp.

    INCYHealth Care
    3.02%
  • 17

    Halozyme Therapeutics Inc

    HALOHealth Care
    2.94%
  • 18

    Qiagen Nv

    QGEN:ASUnknown
    2.89%
  • 19

    Biomarin Pharmaceutical Inc.

    BMRNHealth Care
    2.79%
  • 20

    Exelixis Inc

    EXELHealth Care
    2.72%
  • 21

    Omeros Corp Com

    OMERHealth Care
    2.70%
  • 22

    BioCryst Pharmaceuticals Inc.

    BCRXHealth Care
    2.59%
  • 23

    Neurocrine Biosciences Inc

    NBIXHealth Care
    2.59%
  • 24

    Collegium Pharmaceutical Inc

    COLLHealth Care
    2.57%
  • 25

    Veracyte, Inc.

    VCYTHealth Care
    2.55%
  • 26

    Ptc Therapeutics Inc

    PTCTHealth Care
    2.48%
  • 27

    Sarepta Therapeutics Inc

    SRPTHealth Care
    2.39%
  • 28

    Anaptysbio Inc

    ANABHealth Care
    2.32%
  • 29

    Ardelyx Inc

    ARDXHealth Care
    1.95%
  • 30

    Legend Biotech, Adr

    LEGNHealth Care
    1.57%
  • 31

    Invesco Government & Agency Portfolio, Institutional Class

    AGPXXFinancials
    0.06%
  • 32

    Commonwealth Of Massachusetts 5 03/01/2038

    Other
    0.00%
  • 33

    Essex Portfolio Lp Company Guar 01/31 1.65

    Other
    0.00%
  • 34

    Cigna Group/The Sr Unsecured 05/29 5

    Other
    0.00%