PBE ETF

PBE ETF
$94.94
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BIIB is PBE's largest holding at 5.22% of the fund as of Sep 15, 2026. PBE is Invesco Biotechnology and Genome ETF.

Showing top 34 of 34 holdings · as of Sep 15, 2026
PBE holdings, by weight
#TickerNameWeightCumulativeSharesMkt valueSectorIndustry
1
BIIB
Biogen Inc.Health Care · Biotechnology
5.22%		5.2%97,463$21.16MHealth CareBiotechnology
2
NTRA
Natera IncHealth Care · Biotechnology
5.19%		10.4%63,897$21.02MHealth CareBiotechnology
Sector and industry · Pro
3
GILD
Gilead Sciences
5.13%		15.5%144,633$20.79M
4
RPRX
Royalty Pharma Plc Class A Ordinary Share
5.01%		20.5%346,648$20.32M
5
REGN
Regeneron Pharmaceuticals, Inc.
4.98%		25.5%25,818$20.18M
6—Nvaesrtex Pharmaceuticals Inc
4.95%		30.5%38,921$20.06M
7
ILMN
Illumina, Inc.
4.87%		35.3%95,636$19.74M
8
AMGN
Amgen Inc.
4.53%		39.9%48,651$18.36M
9
SRPT
Sarepta Therapeutics Inc
3.13%		43.0%620,303$12.69M
10
NBIX
Neurocrine Biosciences Inc
2.95%		46.0%76,529$11.96M
11
NVAX
Novavax Inc
2.89%		48.9%1,243,231$11.71M
12
BMRN
Biomarin Pharmaceutical Inc.
2.88%		51.7%177,491$11.66M
13
EXEL
Exelixis Inc
2.87%		54.6%206,910$11.61M
14
PTGX
Protagonist Therapeutics Inc
2.85%		57.5%77,937$11.55M
15
HALO
Halozyme Therapeutics Inc
2.84%		60.3%107,360$11.51M
16
TGTX
Tg Therapeutics Inc
2.82%		63.1%211,761$11.41M
17—Qiagen Nv Ord
2.82%		65.9%268,866$11.43M
18
UTHR
United Therapeutics Corp
2.78%		68.7%22,631$11.25M
19
ARDX
Ardelyx Inc
2.74%		71.5%3,104,786$11.12M
20
INCY
Incyte Corp.
2.71%		74.2%90,477$10.99M
21
VCYT
Veracyte, Inc.
2.69%		76.8%266,490$10.89M
22
ANAB
Anaptysbio Inc
2.67%		79.5%201,066$10.83M
23
ACAD
Acadia Pharmaceuticals Inc
2.64%		82.2%383,915$10.68M
24
RGEN
Repligen Corp
2.63%		84.8%64,594$10.67M
25—Moderna therapeutics
2.62%		87.4%73,884$10.64M
26
PTCT
Ptc Therapeutics Inc
2.60%		90.0%159,733$10.55M
27
VCEL
Vericel Corp
2.57%		92.6%271,539$10.41M
28
LEGN
Legend Biotech Corp
2.53%		95.1%550,991$10.27M
29
COLL
Collegium Pharmaceutical Inc
2.40%		97.5%427,239$9.72M
30
BCRX
BioCryst Pharmaceuticals Inc.
2.39%		99.9%1,193,904$9.69M
31
AGPXX
Invesco Government & Agency Portfolio, Institutional Class
0.10%		100.0%388,818$388.8K
32—Cash &Amp; Equivalents
0.00%		100.0%5,728$5.7K
33—Securities Lending - Bnym
0.00%		100.0%1-
34—Usd Pending Dividends
0.00%		100.0%-$199
Not reported for this fund: share changes.
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PBE ETF All Holdings

PBE holdings total 68 positions. The top 10 holdings account for 46.0% of the fund, led by Biogen Inc. Com at 5.2%, Natera Inc at 5.2%, Gilead Sciences at 5.1%.

PBE portfolio concentration is moderate, with the top 10 representing 46.0% of total assets. The largest sector exposure is Health Care at 92.1%.

PBE sectors provide a detailed breakdown. PBE overlap shows how holdings compare to other funds in your portfolio.

Compare PBE

PBE vs SPYPBE vs QQQPBE vs VOOPBE vs VTIPBE vs IVVPBE vs SCHDPBE vs VYMPBE vs VXUS

PBE ETF Holdings

34 of 68 holdings

  • 1

    Biogen Inc. Com

    BIIBHealth Care
    5.22%
  • 2

    Natera Inc

    NTRAHealth Care
    5.19%
  • 3

    Gilead Sciences

    GILDHealth Care
    5.13%
  • 4

    Royalty Pharma Plc Class A Ordinary Share

    RPD:DUFinancials
    5.01%
  • 5

    Regeneron Pharmaceuticals, Inc.

    REGNHealth Care
    4.98%
  • 6

    Nvaesrtex Pharmaceuticals Inc

    VRTXHealth Care
    4.95%
  • 7

    Illumina, Inc.

    ILMNHealth Care
    4.87%
  • 8

    Amgen Inc.

    AMGNHealth Care
    4.53%
  • 9

    Sarepta Therapeutics Inc

    SRPTHealth Care
    3.13%
  • 10

    Neurocrine Biosciences Inc

    NBIXHealth Care
    2.95%
  • 11

    Novavax Inc

    NVAXHealth Care
    2.89%
  • 12

    Biomarin Pharmaceutical Inc.

    BMRNHealth Care
    2.88%
  • 13

    Exelixis Inc

    EXELHealth Care
    2.87%
  • 14

    Protagonist Therapeutics Inc

    PTGXHealth Care
    2.85%
  • 15

    Halozyme Therapeutics Inc

    HALOHealth Care
    2.84%
  • 16

    Tg Therapeutics Inc Common Stock

    TGTXHealth Care
    2.82%
  • 17

    Qiagen Nv Ord

    QGEN:ASUnknown
    2.82%
  • 18

    United Therapeutics Corp

    UTHRHealth Care
    2.78%
  • 19

    Ardelyx Inc

    ARDXHealth Care
    2.74%
  • 20

    Incyte Corp.

    INCYHealth Care
    2.71%
  • 21

    Veracyte, Inc.

    VCYTHealth Care
    2.69%
  • 22

    Anaptysbio Inc

    ANABHealth Care
    2.67%
  • 23

    Acadia Pharmaceuticals Inc Common Stock Usd 0.0001

    ACADHealth Care
    2.64%
  • 24

    Repligen Corp

    RGENHealth Care
    2.63%
  • 25

    Moderna therapeutics

    MRNAHealth Care
    2.62%
  • 26

    Ptc Therapeutics Inc

    PTCTHealth Care
    2.60%
  • 27

    Vericel Corp

    VCELHealth Care
    2.57%
  • 28

    Legend Biotech Corp

    LEGNHealth Care
    2.53%
  • 29

    Collegium Pharmaceutical Inc

    COLLHealth Care
    2.40%
  • 30

    BioCryst Pharmaceuticals Inc.

    BCRXHealth Care
    2.39%
  • 31

    Invesco Government & Agency Portfolio, Institutional Class

    AGPXXFinancials
    0.10%
  • 32

    Cash &Amp; Equivalents

    Other
    0.00%
  • 33

    Securities Lending - Bnym

    Other
    0.00%
  • 34

    Usd Pending Dividends

    Other
    0.00%